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European Journal of Human Genetics (1)
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Advanced filters: Author: Stella Lanni Clear advanced filters

A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo

Naphthyridine-azaquinolone specifically binds slipped-CAG DNA intermediates, induces contractions of expanded repeats and reduces mutant HTT protein aggregates in cell and animal models of Huntington’s disease.

Masayuki Nakamori
Gagan B. Panigrahi
Christopher E. Pearson
Research14 Feb 2020
Nature Genetics

Volume: 52, P: 146-159
Defining the role of the CGGBP1 protein in FMR1 gene expression

Martina Goracci
Stella Lanni
Elisabetta Tabolacci
Research26 Aug 2015
European Journal of Human Genetics

Volume: 24, P: 697-703

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A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo

Defining the role of the CGGBP1 protein in FMR1 gene expression

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