Nature Search

Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1

Fabio M V Rossi
Stephane Y Corbel
Hermann J Ziltener
Research08 May 2005
Nature Immunology

Volume: 6, P: 626-634
Contribution of hematopoietic stem cells to skeletal muscle

Stéphane Y Corbel
Adrienne Lee
Fabio M V Rossi
Research16 Nov 2003
Nature Medicine

Volume: 9, P: 1528-1532
Reprogramming towards pluripotency requires AID-dependent DNA demethylation

To elucidate regulatory mechanisms involved in reprogramming to generate pluripotent cells from somatic cells, this study generates interspecies heterokaryons (fused mouse ES cells and human fibroblasts) that induce reprogramming efficiently, rapidly and without cell division. SiRNA–mediated knockdown reveals that AID is required for active DNA demethylation and initiation of nuclear reprogramming towards pluripotency in human somatic cells.

Nidhi Bhutani
Jennifer J. Brady
Helen M. Blau
Research21 Dec 2009
Nature

Volume: 463, P: 1042-1047
Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein

Three new red-excitable monomeric fluorescent proteins obtained by structure-guided mutagenesis of mNeptune are described in this work. The authors show the use of one of them, mCardinal, to visualize the differentiation of myoblasts into myocytes in living mice.

Jun Chu
Russell D Haynes
Michael Z Lin
Research16 Mar 2014
Nature Methods

Volume: 11, P: 572-578
Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M

The factors that mediate quiescence of muscle stem cells are unknown. The authors show that Oncostatin M is produced by skeletal muscle, suppresses stem cell proliferation, and that its deletion in muscle results in stem cell depletion and impaired muscle regeneration following injury in mice.

Srinath C. Sampath
Srihari C. Sampath
Helen M. Blau
ResearchOpen Access18 Apr 2018
Nature Communications

Volume: 9, P: 1-9
The microprotein Minion controls cell fusion and muscle formation

Cellular fusion is essential for skeletal muscle development. Here the authors identify Minion as a microprotein required for myoblast fusion and skeletal muscle formation, and show that co-expression of Minion and Myomaker is sufficient to induce cytoskeletal rearrangement and cell fusion even in non-muscle cells.

Qiao Zhang
Ajay A. Vashisht
Srihari C. Sampath
ResearchOpen Access01 Jun 2017
Nature Communications

Volume: 8, P: 1-15
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

In two new studies, Helen Blau and Bradley Olwin and their colleagues show that muscle stem cells in aged mice have an intrinsic defect in their stem cell capacity, contributing to age-related sarcopenia. They also provide mechanistic insight to explain this phenomenon and show that biochemical and biophysical manipulations can overcome the defect, suggesting a possible future route of therapy.

Benjamin D Cosgrove
Penney M Gilbert
Helen M Blau
Research16 Feb 2014
Nature Medicine

Volume: 20, P: 255-264
Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation

Clas B. Johansson
Sawsan Youssef
Helen M. Blau
Research20 Apr 2008
Nature Cell Biology

Volume: 10, P: 575-583
Bone marrow-derived recipient cells in murine transplanted hearts: potential roles and the effect of immunosuppression

Nana Rezai
Stephane Y Corbel
Thomas J Podor
Research20 Jun 2005
Laboratory Investigation

Volume: 85, P: 982-991
Experimental evolution supports the potential of neonicotinoid-pyrethroid combination for managing insecticide resistance in malaria vectors

Marius Gonse Zoh
Jean-Marc Bonneville
Jean-Philippe David
ResearchOpen Access30 Sept 2021
Scientific Reports

Volume: 11, P: 1-16

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