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Correction: Corrigendum: B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

Irene Puga
Montserrat Cols
Andrea Cerutti
Amendments and Corrections21 Jan 2014
Nature Immunology

Volume: 15, P: 205
Mucosal or systemic microbiota exposures shape the B cell repertoire

A mouse model of systemic versus mucosal exposure to microbial taxa reveals that the former provokes a flexible B cell response with a diverse immunoglobulin repertoire, whereas the latter generates a more-restricted response.

Hai Li
Julien P. Limenitakis
Andrew J. Macpherson
Research05 Aug 2020
Nature

Volume: 584, P: 274-278
Checkpoint for gut microbes after birth

The route to the establishment of a beneficial microbial community in the gut after birth is not fully understood. It now emerges that a gut-cell protein in newborn mice shapes the long-term composition of this community.

Andrew J. Macpherson
Stephanie C. Ganal-Vonarburg
News & Views08 Aug 2018
Nature

Volume: 560, P: 436-438
B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

Follicular T cells provide help to B cells to elicit antibody responses. Cerutti and colleagues show that neutrophils provide help to marginal-zone B cells that produce T cell–independent antibodies.

Irene Puga
Montserrat Cols
Andrea Cerutti
Research25 Dec 2011
Nature Immunology

Volume: 13, P: 170-180
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N⁶-carboxymethyllysine

Due to a microbiota-dependent increase in intestinal permeability with age, the gut metabolite N⁶-carboxymethyllysine accumulates in the microglia of mouse and human brains. As a result, microglia display increased oxidative stress and mitochondrial dysfunction.

Omar Mossad
Bérénice Batut
Thomas Blank
Research03 Mar 2022
Nature Neuroscience

Volume: 25, P: 295-305
How nutrition and the maternal microbiota shape the neonatal immune system

This Review discusses the importance of the maternal microbiota in shaping the development of the fetus, with a focus on the developing immune system.

Andrew J. Macpherson
Mercedes Gomez de Agüero
Stephanie C. Ganal-Vonarburg
Reviews12 Jun 2017
Nature Reviews Immunology

Volume: 17, P: 508-517
Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

This Perspective reviews the evidence for and against the existence of a fetal microbiome and concludes that detected microbial signals are most likely the result of contamination, suggesting that the ‘sterile womb’ hypothesis is correct.

Katherine M. Kennedy
Marcus C. de Goffau
Jens Walter
Reviews25 Jan 2023
Nature

Volume: 613, P: 639-649
Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity

Expansion of pro-inflammatory macrophages in the colon occurs early after high-fat diet initiation, prior to macrophage accumulation in the adipose tissue, in a microbiome-dependent fashion. Macrophage depletion systemically and/or exclusively in the colon improves glucose metabolism.

Theresa V. Rohm
Lena Keller
Claudia Cavelti-Weder
ResearchOpen Access19 Apr 2022
Communications Biology

Volume: 5, P: 1-15

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