Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Stephanie Grebinoski Clear advanced filters

  • SABR-IIs are engineered bifunctional receptors that enable CD4+ T cell antigen discovery.

    • Paul M. Zdinak
    • Nishtha Trivedi
    • Alok V. Joglekar
    ResearchOpen Access
    Nature Methods
    Volume: 21, P: 846-856

  • Exhausted T cells are associated with inefficient viral clearance, tumor immunity and response to immunotherapy. Here the authors show CD8+ T cells in the pancreatic islets have a LAG3-promoted ‘restrained’ phenotype resembling exhausted cells but maintain effector functions, and LAG3 expression limits pathology in the nonobese diabetic mouse model of type 1 diabetes.

    • Stephanie Grebinoski
    • Qianxia Zhang
    • Dario A. A. Vignali
    Research
    Nature Immunology
    Volume: 23, P: 868-877

  • The binding of PD-L1 to CD80 on antigen-presenting cells prevents PD-1 ligation on T cells. Therapeutic blockade of the cis-PD-L1–CD80 interaction liberates PD-L1 to bind to PD-1, inhibits autoreactive T cells and robustly alleviates autoimmune symptoms.

    • Stephanie Grebinoski
    • Angela M. Gocher-Demske
    • Dario A. A. Vignali
    News & Views
    Nature Immunology
    Volume: 23, P: 344-346

  • The tumour microenvironment is low in glucose and high in the alternative metabolite lactate, which regulatory T cells are shown here to use, maintaining their ability to suppress effector immune cells.

    • McLane J. Watson
    • Paolo D. A. Vignali
    • Greg M. Delgoffe
    Research
    Nature
    Volume: 591, P: 645-651