Nature Search

The phenotype of MEGF8-related Carpenter syndrome (CRPT2) is refined through the identification of eight new patients

Laura M. Watts
Marta Bertoli
Andrew O. M. Wilkie
ResearchOpen Access17 May 2024
European Journal of Human Genetics

Volume: 32, P: 864-870
Carpenter bee thorax vibration and force generation inform pollen release mechanisms during floral buzzing

Mark Jankauski
Cailin Casey
Stephen Buchmann
ResearchOpen Access05 Aug 2022
Scientific Reports

Volume: 12, P: 1-10
Sudden death in infancy

STEPHEN MAGURA
Research01 Aug 1975
Nature

Volume: 256, P: 519
Runaway coral-algal dysbiosis may be responsible for rapid coral tissue loss

Ashley M. Rossin
Kelsey M. Beavers
Daniel M. Holstein
ResearchOpen Access27 Jan 2026
Scientific Reports

P: 1-14
Nature: the many benefits of ecosystem services

Walter V. Reid
Harold A. Mooney
Zhao Shidong
Correspondence18 Oct 2006
Nature

Volume: 443, P: 749
Dual Localization of β-Glucuronidase in Endoplasmic Reticulum and in Lysosomes

WILLIAM H. FISHMAN
STEPHEN S. GOLDMAN
RONALD DeLELLIS
Research04 Feb 1967
Nature

Volume: 213, P: 457-460
Things are looking up and up

Stephen P. Maran
Books & Arts09 Feb 1989
Nature

Volume: 337, P: 517
The value of the world's ecosystem services and natural capital

Robert Costanza
Ralph d'Arge
Marjan van den Belt
Research15 May 1997
Nature

Volume: 387, P: 253-260
Early warning signals have limited applicability to empirical lake data

Abrupt regime shifts could in theory be predicted from early warning signals. Here, the authors show that true critical transitions are challenging to classify in lake planktonic systems, due to mismatches between trophic levels, and reveal uneven performance of early warning signal detection methods.

Duncan A. O’Brien
Smita Deb
Christopher F. Clements
ResearchOpen Access01 Dec 2023
Nature Communications

Volume: 14, P: 1-14
A canine distemper virus epidemic in Serengeti lions (Panthera leo)

Melody E. Roelke-Parker
Linda Munson
Max J. G. Appel
Research01 Feb 1996
Nature

Volume: 379, P: 441-445
Correction: A canine distemper virus epidemic in Serengeti lions (Panthera leo)

Melody E. Roelke-Parker
Linda Munson
Max J. G. Appel
Amendments and Corrections09 May 1996
Nature

Volume: 381, P: 172
Induction of c-fos-like protein in spinal cord neurons following sensory stimulation

Stephen P. Hunt
Adrian Pini
Gerard Evan
Research13 Aug 1987
Nature

Volume: 328, P: 632-634
Opportunities and challenges for monitoring terrestrial biodiversity in the robotics age

An expert-elicitation process identifies current methodological barriers for monitoring terrestrial biodiversity, and how technological and procedural development of robotic and autonomous systems may contribute to overcoming these challenges.

Stephen Pringle
Martin Dallimer
Zoe G. Davies
ResearchOpen Access22 May 2025
Nature Ecology & Evolution

Volume: 9, P: 1031-1042
Activation of the β1 isozyme of phospholipase C by α subunits of the G_q class of G proteins

Stephen J. Taylor
Ho Zoon Chae
John H. Exton
Research11 Apr 1991
Nature

Volume: 350, P: 516-518
Correction: The structure of the Escherichia coli EF-Tu. EF-Ts complex at 2.5 Å resolution

Takemasa Kawashima
Carmen Berthet-Colominas
Reuben Leberman
Amendments and Corrections09 May 1996
Nature

Volume: 381, P: 172
Thresholds for adding degraded tropical forest to the conservation estate

An analysis of the impact of logging intensity on biodiversity in tropical forests in Sabah, Malaysia, identifies a threshold of tree biomass removal below which logged forests still have conservation value.

Robert M. Ewers
C. David L. Orme
Cristina Banks-Leite
ResearchOpen Access17 Jul 2024
Nature

Volume: 631, P: 808-813
Reproducible image-based profiling with Pycytominer

Pycytominer is a user-friendly, open-source Python package that carries out key bioinformatics steps in image-based profiling.

Erik Serrano
Srinivas Niranj Chandrasekaran
Gregory P. Way
Research03 Mar 2025
Nature Methods

Volume: 22, P: 677-680
Activated GDF11/8 subforms predict cardiovascular events and mortality in humans

The predictive value of blood levels of GDF11/8 proteins in humans for future disease outcomes has been unclear. Here, the authors show that low levels of specific activated GDF11/8 subforms are strongly associated with future cardiovascular events, mortality, and dementia risk.

Ryan G. Walker
Tomohiro Kato
Richard T. Lee
ResearchOpen Access15 Jul 2025
Nature Communications

Volume: 16, P: 1-14
CD22 regulates thymus-independent responses and the lifespan of B cells

Kevin L. Otipoby
Kristin B. Andersson
Edward A. Clark
Research26 Dec 1996
Nature

Volume: 384, P: 634-637
Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

Michael J. Eck
Scott Pluskey
Steven E. Shoelson
Research18 Jan 1996
Nature

Volume: 379, P: 277-280
Developmentally regulated production of platelet-derived growth factor-like molecules

Ronald A. Seifert
Stephen M. Schwartz
Daniel F. Bowen-Pope
Research18 Oct 1984
Nature

Volume: 311, P: 669-671
Transition-state stabilization as a measure of the efficiency of antibody catalysis

Jon D. Stewart
Stephen J. Benkovic
Research01 Jun 1995
Nature

Volume: 375, P: 388-391
Large changes in oceanic nutrient inventories from glacial to interglacial periods

Raja S. Ganeshram
Thomas F. Pedersen
James W. Murray
Research31 Aug 1995
Nature

Volume: 376, P: 755-758
Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc

Stephen M. Dilworth
Charlotte E. P. Brewster
Pier G. Pelicci
Research06 Jan 1994
Nature

Volume: 367, P: 87-90
Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

An integrated analysis of de novo and inherited coding variants in 42,607 individuals with autism spectrum disorder identifies 60 risk genes of which five have not previously been associated with neurodevelopmental disorders.

Xueya Zhou
Pamela Feliciano
Wendy K. Chung
ResearchOpen Access18 Aug 2022
Nature Genetics

Volume: 54, P: 1305-1319
Reply to: Brazilian ethanol expansion subject to limitations

Deepak Jaiswal
Amanda P. De Souza
Stephen P. Long
Research25 Feb 2019
Nature Climate Change

Volume: 9, P: 211-212
Quantifying resilience to recurrent ecosystem disturbances using flow–kick dynamics

Sustainability depends on the resilience of natural, social and engineered systems. This theoretical study quantifies resilience to repeated disturbances, synthesizing understanding of how the sizes of shocks, or ‘kicks’, and recovery, or ‘flows’, contribute to maintaining systems in desirable states.

Katherine Meyer
Alanna Hoyer-Leitzel
Mary Lou Zeeman
Research13 Nov 2018
Nature Sustainability

Volume: 1, P: 671-678
Extraordinary Stability of Enzymes Dried in Trehalose: Simplified Molecular Biology

Camilo Colaço
Shevanti Sen
Bruce Roser
Research01 Sept 1992
Bio/Technology

Volume: 10, P: 1007-1011
Cryo-EM structure of the human THIK-1 K2P K⁺ channel reveals a lower Y gate regulated by lipids and anesthetics

In this study, Rödström et al. use cryo-EM to reveal a range of structural features in THIK-1 K⁺ channel and demonstrate how these features define many functional properties of the channel, thus expanding its potential as a drug target.

Karin E. J. Rödström
Bisher Eymsh
Stephen J. Tucker
ResearchOpen Access26 Feb 2025
Nature Structural & Molecular Biology

Volume: 32, P: 1167-1174
Ribozymes: Stop Making Sense

Stephen M. Edgington
Research01 Mar 1992
Bio/Technology

Volume: 10, P: 256-262
Conserving key coastal areas for mangrove expansion and eco-tourism secures ecosystem services under sea-level rise

Kostantinos A. Stamoulis
Simon J. Pittman
Daniel Mateos-Molina
ResearchOpen Access24 Dec 2025
npj Ocean Sustainability

Volume: 5, P: 1-16
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation

K2P channels are important regulators of cellular electrical activity. Here the authors show how nanobody fragments can be used to detect and modulate TREK2 K2P channel activity to provide insight into the mechanism of gating.

Karin E. J. Rödström
Alexander Cloake
Stephen J. Tucker
ResearchOpen Access16 May 2024
Nature Communications

Volume: 15, P: 1-13
A lower X-gate in TASK channels traps inhibitors within the vestibule

The X-ray crystal structure of the potassium channel TASK-1 reveals the presence of an X-gate, which traps small-molecule inhibitors in the intramembrane vestibule and explains their low washout rates from the channel.

Karin E. J. Rödström
Aytuğ K. Kiper
Elisabeth P. Carpenter
Research29 Apr 2020
Nature

Volume: 582, P: 443-447
Menkes disease mutations and response to early copper histidine treatment

Stephen G. Kaler
Correspondence01 May 1996
Nature Genetics

Volume: 13, P: 21-22
Site-directed mutagenesis shows that tyrosine 248 of carboxypeptidase A does not play a crucial role in catalysis

Stephen J. Gardell
Charles S. Craik
William J. Rutter
Research01 Oct 1985
Nature

Volume: 317, P: 551-555
Family history-taking in community family practice: Implications for genetic screening

Louise S Acheson
Georgia L Wiesner
Kurt C Stange
Research01 May 2000
Genetics in Medicine

Volume: 2, P: 180-185
Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56^lck

Michael J. Eck
Steven E. Shoelson
Stephen C. Harrison
Research01 Mar 1993
Nature

Volume: 362, P: 87-91
Methylphenidate Response, Psychopathology and Tardive Dyskinesia as Predictors of Relapse in Schizophrenia

Jeffrey A. Lieberman
Jose Alvir
John M. Kane
Research01 Oct 1994
Neuropsychopharmacology

Volume: 11, P: 107-118
Functional genomic landscape of acute myeloid leukaemia

Analyses of samples from patients with acute myeloid leukaemia reveal that drug response is associated with mutational status and gene expression; the generated dataset provides a basis for future clinical and functional studies of this disease.

Jeffrey W. Tyner
Cristina E. Tognon
Brian J. Druker
Research17 Oct 2018
Nature

Volume: 562, P: 526-531
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Breast cancer risk for BRCA1/BRCA2 mutation carriers varies depending on other genetic factors. Here, the authors perform a case-only genome-wide association study and highlight novel loci associated with breast cancer risk for BRCA1/BRCA2 mutation carriers.

Juliette Coignard
Michael Lush
Antonis C. Antoniou
ResearchOpen Access17 Feb 2021
Nature Communications

Volume: 12, P: 1-22
Automatic data-driven design and 3D printing of custom ocular prostheses

Manual processes to produce ocular prostheses are time-consuming and yield varying quality. Here, authors present an automatic digital end-to-end process for custom ocular prostheses. It creates shape and appearance from image data of an OCT device and produces them using a full-colour 3D printer.

Johann Reinhard
Philipp Urban
Mandeep S. Sagoo
ResearchOpen Access27 Feb 2024
Nature Communications

Volume: 15, P: 1-14
Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions

Lucilia cuprina is a parasitic blowfly of major economic importance worldwide that feeds on the tissues of animals such as sheep. Here, the authors sequence the genome of L. cuprinaand provide insights into the fly’s molecular biology, interactions with the host animal and insecticide resistance.

Clare A. Anstead
Pasi K. Korhonen
Robin B. Gasser
ResearchOpen Access25 Jun 2015
Nature Communications

Volume: 6, P: 1-11
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Oestrogen negative breast cancer is associated with a poor prognosis. In this study, the authors perform a meta-analysis of 11 breast cancer genome-wide association studies and identify four new loci associated with oestrogen negative breast cancer risk. These findings may aid in stratifying patients in the clinic.

Fergus J. Couch
Karoline B. Kuchenbaecker
Antonis C. Antoniou
ResearchOpen Access27 Apr 2016
Nature Communications

Volume: 7, P: 1-13
The Alternative Pathway of Complement Activation in the Neonate

Peter A Feinstein
Stephen R Kaplan
Research01 Oct 1975
Pediatric Research

Volume: 9, P: 803-806
The impact of exercise on gene regulation in association with complex trait genetics

It is known that exercise influences many human traits, but not which tissues and genes are most important. This study connects transcriptome data collected across 15 tissues during exercise training in rats as part of the Molecular Transducers of Physical Activity Consortium with human data to identify traits with similar tissue specific gene expression signatures to exercise.

Nikolai G. Vetr
Nicole R. Gay
Stephen B. Montgomery
ResearchOpen Access01 May 2024
Nature Communications

Volume: 15, P: 1-14
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus

SNP rs17713054 in the 3p21.31 COVID-19 risk locus is identified as a probable causative variant for disease association. Chromatin conformation and gene expression data indicate that LZTFL1 is impacted by rs17713054 in pulmonary epithelial cells.

Damien J. Downes
Amy R. Cross
Jim R. Hughes
Research04 Nov 2021
Nature Genetics

Volume: 53, P: 1606-1615
Gestational diabetes mellitus: does an effective prevention strategy exist?

Gestational diabetes mellitus (GDM) is associated with considerable risks to both the mother and developing baby. In this article, the authors review the evidence from randomized controlled trials for strategies designed to prevent GDM, such as lifestyle modification, dietary supplementation and pharmacological approaches.

Rochan Agha-Jaffar
Nick Oliver
Stephen Robinson
Reviews24 Jun 2016
Nature Reviews Endocrinology

Volume: 12, P: 533-546
Gain-of-function mutations in KCNK3 cause a developmental disorder with sleep apnea

Heterozygous de novo gain-of-function mutations in KCNK3, which encodes the two-pore-domain K⁺ channel TASK-1, cause a channelopathy characterized by developmental delay with sleep apnea.

Janina Sörmann
Marcus Schewe
Stephen J. Tucker
ResearchOpen Access04 Oct 2022
Nature Genetics

Volume: 54, P: 1534-1543
MDC1 is a mediator of the mammalian DNA damage checkpoint

Grant S. Stewart
Bin Wang
Stephen J. Elledge
Research27 Feb 2003
Nature

Volume: 421, P: 961-966
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

Over 170 susceptibility loci have been identified by genome-wide association studies in breast cancer. Here, the authors interrogated the role of risk-associated variants from non-breast tissue, and using expression quantitative trait loci, identify potential target genes of known breast cancer susceptibility variants, as well as 11 regions not previously known to be associated with breast cancer risk.

Manuel A. Ferreira
Eric R. Gamazon
Georgia Chenevix-Trench
ResearchOpen Access15 Apr 2019
Nature Communications

Volume: 10, P: 1-18

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