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Showing 1–6 of 6 results
Advanced filters: Author: Steve Rockman Clear advanced filters

  • The immunology of Indigenous populations is generally understudied outside the context of diseases that are prevalent in these communities. Here the authors identify prevalence of influenza CD8+ T cell epitopes in an Indigenous Australian population expressing the susceptibility allomorph HLA A*24:02 and validate immunodominance of some of these epitopes in mice.

    • Luca Hensen
    • Patricia T. Illing
    • Katherine Kedzierska
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-20

  • Cross-protective responses across all strains of influenza virus (IAV, IBV and ICV) are a key goal of universal vaccines against influenza. Kedzierska and colleagues identify cytotoxic T cells present in blood and lungs of healthy people that are directed against all strains of influenza virus.

    • Marios Koutsakos
    • Patricia T. Illing
    • Katherine Kedzierska
    Research
    Nature Immunology
    Volume: 20, P: 613-625

  • Influenza B viruses are linked to significant morbidity and mortality, and yet their immunobiology is comparatively poorly understood. Here Menon et al identify influenza B virus-specific CD8+ T cell epitopes and characterise these in adults, children and the elderly.

    • Tejas Menon
    • Patricia T. Illing
    • Katherine Kedzierska
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21

  • The SARS-CoV-2 pandemic has seen a notable global reduction in influenza cases of both influenza A and B viruses. In particular, the B/Yamagata lineage has not been isolated from April 2020 to August 2021, suggesting that this influenza lineage may have become extinct, which may provide opportunities for improving availability and effectiveness of influenza vaccines.

    • Marios Koutsakos
    • Adam K. Wheatley
    • Steve Rockman
    Comments & Opinion
    Nature Reviews Microbiology
    Volume: 19, P: 741-742