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Advanced filters: Author: Steven C. Brodar Clear advanced filters

  • The role of ciliary/centriolar components in the postnatal brain is unclear. Here, the authors show via ablation of Pcm1 in mice that degenerative ciliary/centriolar phenotypes induce neuroanatomical and behavioral changes. Sequencing of PCM1 in human cohorts and zebrafish in vivo complementation suggests PCM1 mutations can contribute to schizophrenia.

    • Tanner O. Monroe
    • Melanie E. Garrett
    • Nicholas Katsanis
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14