Nature Search

A mouse brain atlas based on dendritic microenvironments

The authors developed a mouse brain atlas using local dendritic morphological patterns from 101,136 neurons. This representation not only improves anatomical precision but also uncovers associations between local dendritic architecture and long-range neuronal projections.

Yufeng Liu
Sujun Zhao
Hanchuan Peng
ResearchOpen Access24 Nov 2025
Nature Neuroscience

Volume: 29, P: 111-122
Personal, social, and natural co-exposure pattern and plasma proteins in cardiometabolic diseases

The mixed effects of personal, social, and environmental exposures on cardiometabolic health are still poorly understood. Here, the authors show that social deprivation within specific co-exposure patterns poses the greatest risk, with immune and inflammatory responses as key mediators.

Xuewei Tang
Huan Xu
Xing Zhao
ResearchOpen Access25 Nov 2025
Nature Communications

Volume: 16, P: 1-11
Neuronal diversity and stereotypy at multiple scales through whole brain morphometry

Here the authors analyzed 3.7 petavoxels of 3D imaging data from 204 mouse brains, aiming to comprehensively characterize diverse morphological and modular patterns conserved across six spatial scales of mouse brain anatomy, ranging from the whole-brain scale to synaptic levels.

Yufeng Liu
Shengdian Jiang
Hanchuan Peng
ResearchOpen Access26 Nov 2024
Nature Communications

Volume: 15, P: 1-23
Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells

Dendritic cells instruct different types of T cell responses depending on the types of microbial ligands sensed. Here the authors show that dendritic cells stimulated via Dectin-1 receptor upregulate TNFSF15 and OX40L and induce T helper 9 response and efficient antitumour immunity in mouse models.

Yinghua Zhao
Xiao Chu
Siqing Wang
ResearchOpen Access05 Aug 2016
Nature Communications

Volume: 7, P: 1-12
Morphological diversity of single neurons in molecularly defined cell types

Sparse labelling and whole-brain imaging are used to reconstruct and classify brain-wide complete morphologies of 1,741 individual neurons in the mouse brain, revealing a dependence on both brain region and transcriptomic profile.

Hanchuan Peng
Peng Xie
Hongkui Zeng
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 174-181
MYC reshapes CTCF-mediated chromatin architecture in prostate cancer

The functional link between MYC and CTCF in prostate cancer remains to be investigated. Here, the authors highlight the role of MYC in rewiring chromatin architecture by interacting with CTCF protein.

Zhao Wei
Song Wang
Haiyang Guo
ResearchOpen Access30 Mar 2023
Nature Communications

Volume: 14, P: 1-15
IL-33 drives the antitumor effects of dendritic cells via the induction of Tc9 cells

Ning Liu
Yuxue Jiang
Siqing Wang
Research01 Oct 2018
Cellular & Molecular Immunology

Volume: 16, P: 644-651
Pulsed Laser Beam Welding of Pd₄₃Cu₂₇Ni₁₀P₂₀ Bulk Metallic Glass

Ling Shao
Amit Datye
Jan Schroers
ResearchOpen Access11 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Dectin-1 stimulates IL-33 expression in dendritic cells via upregulation of IRF4

Dongjiao Wang
Sujun Gao
Siqing Wang
Research14 Mar 2018
Laboratory Investigation

Volume: 98, P: 708-714
Facilitating integrative and personalized oncology omics analysis with UCSCXenaShiny

UCSCXenaShiny integrates multidimensional data for robust and personalized pan-cancer analysis pipelines, enabling in-depth cancer data exploration in diverse scenarios.

Shensuo Li
Yuzhong Peng
Shixiang Wang
ResearchOpen Access28 Sept 2024
Communications Biology

Volume: 7, P: 1-9
A multimodal cell census and atlas of the mammalian primary motor cortex

The BRAIN Initiative Cell Census Network has constructed a multimodal cell census and atlas of the mammalian primary motor cortex in a landmark effort towards understanding brain cell-type diversity, neural circuit organization and brain function.

Edward M. Callaway
Hong-Wei Dong
Susan Sunkin
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 86-102
Ruxolitinib plus steroids for acute graft versus host disease: a multicenter, randomized, phase 3 trial

Liping Dou
Yanli Zhao
Daihong Liu
ResearchOpen Access23 Oct 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-11
CTNet: a convolutional transformer network for EEG-based motor imagery classification

Wei Zhao
Xiaolu Jiang
Sujun Weng
ResearchOpen Access30 Aug 2024
Scientific Reports

Volume: 14, P: 1-22
Fourth-generation chimeric antigen receptor T-cell therapy is tolerable and efficacious in treatment-resistant rheumatoid arthritis

Yujing Li
Sujun Li
Zhu Chen
CorrespondenceOpen Access09 Jan 2025
Cell Research

Volume: 35, P: 220-223
Apigenin attenuates atherosclerosis and non-alcoholic fatty liver disease through inhibition of NLRP3 inflammasome in mice

Zheng Lu
Lu Liu
Mingyang Li
ResearchOpen Access17 May 2023
Scientific Reports

Volume: 13, P: 1-11
Galectin-3 critically mediates the hepatoprotection conferred by M2-like macrophages in ACLF by inhibiting pyroptosis but not necroptosis signalling

Li Bai
Wang Lu
Yu Chen
ResearchOpen Access08 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-10
A Multi-Scale Neuron Morphometry Dataset from Peta-voxel Mouse Whole-Brain Images

Shengdian Jiang
Sujun Zhao
Hanchuan Peng
ResearchOpen Access23 Apr 2025
Scientific Data

Volume: 12, P: 1-13
ATP7B R778L mutant hepatocytes resist copper toxicity by activating autophagy and inhibiting necroptosis

Shan Tang
Chen Liang
Sujun Zheng
ResearchOpen Access16 Sept 2023
Cell Death Discovery

Volume: 9, P: 1-11
Effect of CO₂ injection pressure on enhanced coal seam gas extraction

Gang Bai
Jun Su
Jundian Chen
ResearchOpen Access28 Oct 2024
Scientific Reports

Volume: 14, P: 1-15
Coordination of carbon and nitrogen accumulation and translocation of winter wheat plant to improve grain yield and processing quality

Xin Huang
Chenyang Wang
Dongyun Ma
ResearchOpen Access25 Jun 2020
Scientific Reports

Volume: 10, P: 1-11
G9A promotes tumor cell growth and invasion by silencing CASP1 in non-small-cell lung cancer cells

Tianhao Huang
Peng Zhang
Fan Zhang
ResearchOpen Access06 Apr 2017
Cell Death & Disease

Volume: 8, P: e2726

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