Nature Search

Introduction of Transmembrane Inner Ear (tmie) Gene Can Recover the Hearing Impairment and Abnormal Behavior in the Circling Mouse

Mi Jung Shin
Jeong-Han Lee
Zae Young Ryoo
ResearchOpen Access28 Jul 2008
Nature Precedings

P: 1
Characterization of a brain tumor cell line established from transgenic mice expressing the vasopressin SV-40 T antigen

Sung Hyun Kim
Myoung Ok Kim
Zae Young Ryoo
ResearchOpen Access01 Jun 2006
Experimental & Molecular Medicine

Volume: 38, P: 196-202
Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice

The biological mechanisms regulating blood-brain barrier integrity remain unclear. Here, the authors identify microglial NLRP3-gasdermin D signaling as a driver of blood-brain barrier disruption during peripheral inflammation in mice, mediated by CXCL-dependent neutrophil recruitment.

Sung-Hyun Yoon
Chae youn Kim
Je-Wook Yu
ResearchOpen Access15 Jan 2025
Nature Communications

Volume: 16, P: 1-21
Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

Tewis Bouwmeester
Sung-Hyun Kim
Eddy M. De Robertis
Research15 Aug 1996
Nature

Volume: 382, P: 595-601
White Light Emission from Blue InGaN LED with Fluorescent Conjugated Polymer Blends

Hong Jeong Yu
Kwanhwi Park
Sung Hyun Kim
Research28 Sept 2009
Polymer Journal

Volume: 41, P: 1076-1079
Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

Brain organoids derived from human pluripotent stem cells can model human brain development and disease, though current culture systems fail to ensure reliable production of high-quality organoids. Here the authors combine human brain extracellular matrix and culture in a microfluidic device to promote structural and functional maturation of human brain organoids.

Ann-Na Cho
Yoonhee Jin
Seung-Woo Cho
ResearchOpen Access05 Aug 2021
Nature Communications

Volume: 12, P: 1-23
Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase

Hee Sun Byun
Minho Won
Gang Min Hur
ResearchOpen Access20 Apr 2008
Experimental & Molecular Medicine

Volume: 40, P: 186-195
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4

Krüppel-like factor 4 (Klf4) promotes the self-renewal of embryonic stem cells, but how Klf4 itself is regulated is unclear. ERK1 and ERK2 are now found to phosphorylate Klf4, targeting it for degradation via the ubiquitin-proteasome pathway and promoting cellular differentiation.

Myoung Ok Kim
Sung-Hyun Kim
Zigang Dong
Research05 Feb 2012
Nature Structural & Molecular Biology

Volume: 19, P: 283-290
Validation of the revised diagnostic criteria for primary plasma cell leukemia by the Korean Multiple Myeloma Working Party

Sung-Hoon Jung
Kihyun Kim
Je-Jung Lee
ResearchOpen Access21 Nov 2022
Blood Cancer Journal

Volume: 12, P: 1-6
Over-expression of extracellular superoxide dismutase in mouse synovial tissue attenuates the inflammatory arthritis

Dong Hoon Yu
Jun Koo Yi
Zae Young Ryoo
ResearchOpen Access21 Jun 2012
Experimental & Molecular Medicine

Volume: 44, P: 529-535
Versatile human cardiac tissues engineered with perfusable heart extracellular microenvironment for biomedical applications

The application of engineered cardiac tissues is limited due to their immaturity and lack of functionality. Here, the authors develop an integrated culture platform featuring heart extracellular matrix cultured in a microfluidic chip to facilitate cardiac tissue development for versatile biomedical applications.

Sungjin Min
Suran Kim
Seung-Woo Cho
ResearchOpen Access22 Mar 2024
Nature Communications

Volume: 15, P: 1-22
Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids

The culture of gastrointestinal organoids relies on Matrigel that has several drawbacks for clinical application. Here, the authors report the feasibility of gastrointestinal tissue-mimetic matrices as effective alternatives to Matrigel for organoid culture and transplantation.

Suran Kim
Sungjin Min
Seung-Woo Cho
ResearchOpen Access30 Mar 2022
Nature Communications

Volume: 13, P: 1-21
Magnetotactic molecular architectures from self-assembly of β-peptide foldamers

Controlling organic materials with magnetic fields in a dynamic fashion is a challenging task. Here, the authors show that synthetic ß-peptide foldamers can be rotated at will under a dynamic magnetic field and that this can be extended to macroscopic scale objects containing these materials.

Sunbum Kwon
Beom Jin Kim
Hee-Seung Lee
ResearchOpen Access29 Oct 2015
Nature Communications

Volume: 6, P: 1-7
Control of plant germline proliferation by SCF^FBL17 degradation of cell cycle inhibitors

A newly discovered F-box protein of Arabidopsis thaliana that promotes twin sperm cell production is identified. The protein, FBL17, targets KRP7, an Arabidopsis inhibitor of CDKA1, for proteasome-dependent degradation, allowing germ cell division and twin sperm cell production.

Hyo Jung Kim
Sung Aeong Oh
Hong Gil Nam
Research23 Oct 2008
Nature

Volume: 455, P: 1134-1137
A synthetic microbial biosensor for high-throughput screening of lactam biocatalysts

Efficient biosynthesis of lactams is still undesirable due to lacking of suitable enzyme. Here, the authors develop a sensitive transcription factor-based biosensor for high-throughput screening of marine metagenome and find a cyclase that can cyclize ω-amino fatty acids to lactam.

Soo-Jin Yeom
Moonjeong Kim
Seung-Goo Lee
ResearchOpen Access29 Nov 2018
Nature Communications

Volume: 9, P: 1-12
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy

Immunotherapy is offering patients with cancer new therapy options. Here, the authors report on the crystal structures of some of these therapies bound to their targets.

Ju Yeon Lee
Hyun Tae Lee
Yong-Seok Heo
ResearchOpen Access31 Oct 2016
Nature Communications

Volume: 7, P: 1-10
Less strained and more efficient GaN light-emitting diodes with embedded silica hollow nanospheres

Jonghak Kim
Heeje Woo
Euijoon Yoon
ResearchOpen Access13 Nov 2013
Scientific Reports

Volume: 3, P: 1-7
An isotopically distinct Zealandia–Antarctic mantle domain in the Southern Ocean

A separate mantle domain, distinct from both the Pacific and Indian domains, exists beneath the Southern Ocean, according to isotope compositions of samples from the Australian–Antarctic ridge.

Sung-Hyun Park
Charles H. Langmuir
Peter J. Michael
Research28 Jan 2019
Nature Geoscience

Volume: 12, P: 206-214
Validation of the 2022 European LeukemiaNet risk stratification for acute myeloid leukemia

Ga-Young Song
Hyeon-Jong Kim
Dennis Dong Hwan Kim
ResearchOpen Access12 Apr 2024
Scientific Reports

Volume: 14, P: 1-10
Allogeneic hematopoietic cell transplantation can overcome the adverse prognosis indicated by secondary-type mutations in de novo acute myeloid leukemia

Ga-Young Song
TaeHyung Kim
Dennis Dong Hwan Kim
Research23 Sept 2022
Bone Marrow Transplantation

Volume: 57, P: 1810-1819
Porous 3D Prussian blue/cellulose aerogel as a decorporation agent for removal of ingested cesium from the gastrointestinal tract

Ilsong Lee
Sung-Hyun Kim
Yun Suk Huh
ResearchOpen Access14 Mar 2018
Scientific Reports

Volume: 8, P: 1-14
Epsin1 modulates synaptic vesicle retrieval capacity at CNS synapses

Jae Won Kyung
Jae Ryul Bae
Sung Hyun Kim
ResearchOpen Access25 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
Roll-to-Roll sputtered ITO/Cu/ITO multilayer electrode for flexible, transparent thin film heaters and electrochromic applications

Sung-Hyun Park
Sang-Mok Lee
Han-Ki Kim
ResearchOpen Access22 Sept 2016
Scientific Reports

Volume: 6, P: 1-12
Volumetric lung nodule segmentation using adaptive ROI with multi-view residual learning

Muhammad Usman
Byoung-Dai Lee
Yeong-Gil Shin
ResearchOpen Access30 Jul 2020
Scientific Reports

Volume: 10, P: 1-15
Adaptor Protein 2 (AP-2) complex is essential for functional axogenesis in hippocampal neurons

Jae Won Kyung
In Ha Cho
Sung Hyun Kim
ResearchOpen Access31 Jan 2017
Scientific Reports

Volume: 7, P: 1-13
Molecular insights into regulatory RNAs in the cellular machinery

Sumin Yang
Sung-Hyun Kim
Jae-Yeol Joo
ReviewsOpen Access14 Jun 2024
Experimental & Molecular Medicine

Volume: 56, P: 1235-1249
Molecular landscape of long noncoding RNAs in brain disorders

Sumin Yang
Key-Hwan Lim
Jae-Yeol Joo
Reviews10 Nov 2020
Molecular Psychiatry

Volume: 26, P: 1060-1074

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