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Acta Pharmacologica Sinica (2)
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Showing 1–4 of 4 results

Advanced filters: Author: Sunny Guin Clear advanced filters

Targeting glycogen metabolism in bladder cancer

Ritterson Lew et al. discuss the role of glycogen metabolism in urothelial bladder cancer development and progression. They describe how alterations of enzymatic functions in this pathway influence cancer viability and consider possible future strategies for targeting the glycogen metabolism and relevant safety aspects.

Carolyn Ritterson Lew
Sunny Guin
Dan Theodorescu
Reviews26 May 2015
Nature Reviews Urology

Volume: 12, P: 383-391
Discovery and characterization of small molecules that target the GTPase Ral

Using a structure-based approach, small molecule inhibitors that selectively target the GTPase Ral are identified and characterized; these first-generation inhibitors will be valuable tools for elucidating the Ral signalling pathway and constitute a step towards developing Ral-specific agents for cancer therapy.

Chao Yan
Degang Liu
Dan Theodorescu
Research14 Sept 2014
Nature

Volume: 515, P: 443-447
The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer

Sunny Guin
Dan Theodorescu
Reviews05 Jan 2015
Acta Pharmacologica Sinica

Volume: 36, P: 291-297
Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy

Ming-Hai Wang
Snehal S Padhye
Yong-qing Zhou
Reviews09 Aug 2010
Acta Pharmacologica Sinica

Volume: 31, P: 1181-1188