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Showing 1–6 of 6 results

Advanced filters: Author: Surojit Biswas Clear advanced filters

Publisher Correction: Single-sequence protein structure prediction using a language model and deep learning

Ratul Chowdhury
Nazim Bouatta
Mohammed AlQuraishi
Amendments and Corrections17 Oct 2022
Nature Biotechnology

Volume: 40, P: 1692
Low-N protein engineering with data-efficient deep learning

A deep-learning-guided approach enables protein engineering using only a small number (‘low N’) of functionally characterized variants of target proteins.

Surojit Biswas
Grigory Khimulya
George M. Church
Research07 Apr 2021
Nature Methods

Volume: 18, P: 389-396
Unified rational protein engineering with sequence-based deep representation learning

UniRep learns fundamental protein features from millions of amino-acid sequences using a recurrent neural network. This summary of features can then be used for protein engineering.

Ethan C. Alley
Grigory Khimulya
George M. Church
Research21 Oct 2019
Nature Methods

Volume: 16, P: 1315-1322
Single-sequence protein structure prediction using a language model and deep learning

RGN2 predicts a protein’s structure from its sequence without a multiple sequence alignment.

Ratul Chowdhury
Nazim Bouatta
Mohammed AlQuraishi
Research03 Oct 2022
Nature Biotechnology

Volume: 40, P: 1617-1623
Tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes

Global patterns of gene transcription can be represented with reduced dimensionality. Here, the authors devise a method called Tradict that learns and uses 100 marker genes to predict transcriptome-wide pathway expression levels and patterns that reflect cell activity and state.

Surojit Biswas
Konstantin Kerner
Philip A. Wigge
ResearchOpen Access05 May 2017
Nature Communications

Volume: 8, P: 1-10
The evening complex coordinates environmental and endogenous signals in Arabidopsis

The evening complex coordinates plant growth and environmental signalling with the circadian clock. Here, a comprehensive dataset of direct transcriptional targets of the evening complex uncovers a high-quality global regulatory network.

Daphne Ezer
Jae-Hoon Jung
Philip A. Wigge
Research26 Jun 2017
Nature Plants

Volume: 3, P: 1-12