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Showing 1–6 of 6 results

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Premature skewing of T cell receptor clonality and delayed memory expansion in HIV-exposed infants

Here, Dzanibe et al show that in utero HIV/ARV exposure sequentially disrupts infant immunologic trajectories, beginning with NK cells that predict vaccine antibody responses and followed by delayed T cell memory maturation linked to skewed TCR clonality.

Sonwabile Dzanibe
Aaron J. Wilk
Clive M. Gray
ResearchOpen Access14 May 2024
Nature Communications

Volume: 15, P: 1-15
Convergent somatic mutations in metabolism genes in chronic liver disease

Whole-genome sequencing analysis of somatic mutations in liver samples from patients with chronic liver disease identifies driver mutations in metabolism-related genes such as FOXO1, and shows that these variants frequently exhibit convergent evolution.

Stanley W. K. Ng
Foad J. Rouhani
Peter J. Campbell
Research13 Oct 2021
Nature

Volume: 598, P: 473-478
Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cells

Marie E. Egan
Judith Glöckner-Pagel
Michael J. Caplan
Research01 May 2002
Nature Medicine

Volume: 8, P: 485-492
Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma

Tracy A. Marko
Ghaidan A. Shamsan
David A. Largaespada
ResearchOpen Access14 Dec 2016
Scientific Reports

Volume: 6, P: 1-11
Novel quantitative pigmentation phenotyping enhances genetic association, epistasis, and prediction of human eye colour

Andreas Wollstein
Susan Walsh
Manfred Kayser
ResearchOpen Access27 Feb 2017
Scientific Reports

Volume: 7, P: 1-11
The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study

Rachel L O’Connell
Tim Rattay
Mohammed Mustafa
ResearchOpen Access29 Mar 2019
British Journal of Cancer

Volume: 120, P: 883-895