This Review integrates discussion of well-established mechanisms that are known to underlie the 'fetal origins hypothesis' of hypertension with examination of mechanisms for which data continue to emerge. Set in the context of implications for public health, the authors suggest that monitoring the blood pressure, renal function and body weight of at-risk children might help to reduce the likelihood of kidney and cardiovascular disease developing in later life.
- David JP Barker
- Susan P Bagby
- Mark A Hanson
