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Understanding metastasis mixed-treatment responses through genomic analyses

Susana Garcia-Recio
Paola Zagami
Charles M. Perou
ResearchOpen Access30 Jan 2025
npj Breast Cancer

Volume: 11, P: 1-8
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis

Perou and colleagues perform genomic, transcriptomic and epigenetic analyses on pairs of primary and metastatic breast tumors, detecting subtype switching and changes in immune signatures and DNA methylation patterns associated with metastasis.

Susana Garcia-Recio
Toshinori Hinoue
Charles M. Perou
ResearchOpen Access30 Dec 2022
Nature Cancer

Volume: 4, P: 128-147
Molecular signatures of in situ to invasive progression for basal-like breast cancers: An integrated mouse model and human DCIS study

Aatish Thennavan
Susana Garcia-Recio
Charles M. Perou
ResearchOpen Access18 Jul 2022
npj Breast Cancer

Volume: 8, P: 1-13

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