REEP domain-containing proteins generate membrane curvature, and some are known to shape the endoplasmic reticulum (ER). Here, the authors show that four understudied members, REEPs 1-4, localize to vesicles that appear to bud out of, and fuse back with, ER.
- Yoko Shibata
- Emily E. Mazur
- Tom A. Rapoport