Nature Search

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

Lucas A. Tomko
Ryan C. Hill
Suzanne M. Ponik
ResearchOpen Access28 Aug 2018
Scientific Reports

Volume: 8, P: 1-11
Obesity and breast density enhance immune exclusion in the primary tumor microenvironment and promote breast cancer metastasis

Abbey E. Williams
Erica J. Hoffmann
Suzanne M. Ponik
ResearchOpen Access28 Feb 2026
Oncogene

Volume: 45, P: 1057-1064
A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells

A prior live-cell exosome reporter showed dim fluorescence and could not be expressed stably, limiting its usefulness. Here the authors stabilise the reporter to allow long-term tracking of exosomes, and incorporate a second fluorophore to visualise the entire exosome lifecycle.

Bong Hwan Sung
Ariana von Lersner
Alissa M. Weaver
ResearchOpen Access29 Apr 2020
Nature Communications

Volume: 11, P: 1-15
In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging

Joseph M. Szulczewski
David R. Inman
Patricia J. Keely
ResearchOpen Access25 May 2016
Scientific Reports

Volume: 6, P: 1-9
The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis

Longmore and colleagues show that in cancer cells that have undergone epithelial-to-mesenchymal transition (EMT), activation of the collagen I receptor DDR2 results in ERK2-dependent maintenance of the protein levels and activity of the EMT inducer SNAIL1, thus facilitating cancer cell invasion and metastasis.

Kun Zhang
Callie A. Corsa
Gregory D. Longmore
Research05 May 2013
Nature Cell Biology

Volume: 15, P: 677-687
Correction: Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics

Tadashi Iida
Yasuyuki Mizutani
Atsushi Enomoto
Amendments and Corrections04 May 2022
Oncogene

Volume: 41, P: 3302
Engineering the bone metastatic prostate cancer niche through a microphysiological system to report patient-specific treatment response

The authors developed a patient-specific microphysiological system using the LumeNEXT microfluidic platform to more accurately recreate the prostate cancer metastatic bone tumor microenvironment.

Cristina Sánchez-de-Diego
Ravi Chandra Yada
Sheena C. Kerr
ResearchOpen Access01 Jul 2025
Communications Biology

Volume: 8, P: 1-22
Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics

Tadashi Iida
Yasuyuki Mizutani
Atsushi Enomoto
Research13 Apr 2022
Oncogene

Volume: 41, P: 2764-2777
Dynamic interactions between the extracellular matrix and estrogen activity in progression of ER+ breast cancer

Fatou Jallow
Kathleen A. O’Leary
Linda A. Schuler
Research12 Aug 2019
Oncogene

Volume: 38, P: 6913-6925

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Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

Obesity and breast density enhance immune exclusion in the primary tumor microenvironment and promote breast cancer metastasis

A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells

In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging

The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis

Correction: Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics

Engineering the bone metastatic prostate cancer niche through a microphysiological system to report patient-specific treatment response

Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to chemotherapeutics

Dynamic interactions between the extracellular matrix and estrogen activity in progression of ER+ breast cancer

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