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Advanced filters: Author: Svenja Vinke Clear advanced filters

Engineered base editors with reduced bystander editing through directed evolution

Base editors are made more precise through deaminase and gRNA engineering.

Ramiro M. Perrotta
Svenja Vinke
George M. Church
ResearchOpen Access18 Dec 2025
Nature Biotechnology

P: 1-10
A swapped genetic code prevents viral infections and gene transfer

A study details the creation of an Escherichia coli genetically recoded organism that is resistant to viral infection, and describes a further modification that keeps the organism and its genetic information biocontained.

Akos Nyerges
Svenja Vinke
George M. Church
Research15 Mar 2023
Nature

Volume: 615, P: 720-727

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Engineered base editors with reduced bystander editing through directed evolution

A swapped genetic code prevents viral infections and gene transfer

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