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Nature Chemical Biology (2)

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Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Dimitrios Anastasiou
Yimin Yu
Matthew G Vander Heiden
Amendments and Corrections26 Nov 2012
Nature Chemical Biology

Volume: 8, P: 1008
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

A small-molecule activator specific for PKM2 binds to a site distinct from the endogenous activator fructose-1,6-bisphosphate, promoting tetramerization and constitutive activation of PKM2, to inhibit xenograft tumor growth in mice.

Dimitrios Anastasiou
Yimin Yu
Matthew G Vander Heiden
Research26 Aug 2012
Nature Chemical Biology

Volume: 8, P: 839-847

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Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

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