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Showing 1–3 of 3 results
Advanced filters: Author: Swarna Reddy Clear advanced filters

  • In a phase 1 dose-escalation study including 11 patients with heart failure who were followed for 12 months, delivery of a cardiotropic adeno-associated viral vector designed to deliver constitutively active protein phosphatase 1 inhibitor 1 to the heart was well tolerated and showed preliminary evidence of efficacy.

    • Timothy D. Henry
    • Eugene S. Chung
    • Roger J. Hajjar
    ResearchOpen Access
    Nature Medicine
    Volume: 31, P: 3845-3852

  • The Impact of Genomic Variation on Function Consortium is combining single-cell mapping, genomic perturbations and predictive modelling to investigate relationships between human genomic variation, genome function and phenotypes and will provide an open resource to the community.

    • Jesse M. Engreitz
    • Heather A. Lawson
    • Ella K. Samer
    Reviews
    Nature
    Volume: 633, P: 47-57