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Advanced filters: Author: Swasti Raychaudhuri Clear advanced filters

Kingdom-specific lipid unsaturation calibrates sequence evolution in membrane arm subunits of eukaryotic respiratory complexes

Here the authors show that lipid exposed surfaces of protein sequences in membrane-embedded Respiratory Complexes experience selection pressure due to cardiolipin unsaturation. This highlights the role of lipid-protein interactions in evolution, and their possible roles in mitochondrial diseases.

Pooja Gupta
Sristi Chakroborty
Swasti Raychaudhuri
ResearchOpen Access27 Feb 2025
Nature Communications

Volume: 16, P: 1-20
Firefly luciferase mutants as sensors of proteome stress

Destabilized mutants of firefly luciferase are characterized as sensors for protein homeostasis (proteostasis). Their use as tools for comparisons of proteostasis capacity is demonstrated in cells and in Caenorhabditis elegans.

Rajat Gupta
Prasad Kasturi
Swasti Raychaudhuri
Research04 Sept 2011
Nature Methods

Volume: 8, P: 879-884
Cytoplasmic sequestration of the RhoA effector mDiaphanous1 by Prohibitin2 promotes muscle differentiation

Amena Saleh
Gunasekaran Subramaniam
Jyotsna Dhawan
ResearchOpen Access05 Jun 2019
Scientific Reports

Volume: 9, P: 1-17

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