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Showing 1–5 of 5 results
Advanced filters: Author: Sylvia Erhardt Clear advanced filters

  • Fungal cryptochromes are photoreceptors that regulate DNA damage, cell development, and the circadian clock. Here, Landmark et al. show that a fungal cryptochrome-like photolyase regulates light- and stress-activated genes and relocates from nuclei to mitochondria in response to oxidative stress.

    • Alexander Landmark
    • Tim Rudolf
    • Reinhard Fischer
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-17

  • Human centromeres contain a small chromatin region with low levels of DNA cytosine methylation that resides with CENP-A. Salinas-Luypaert et al. find a role of DNA methylation in maintaining the size and function of centromeres by controlling the binding affinity of key centromere components.

    • Sylvia Erhardt
    News & Views
    Nature Genetics
    Volume: 57, P: 2352-2354

  • Accurate segregation of genetic information during cell division relies on a multiprotein complex called the kinetochore, whose formation requires specialized centromeric chromatin. Two papers in this issue of Nature Cell Biology identify a multitude of new vertebrate kinetochore proteins that provide insight into the link between centromeric chromatin and the kinetochore, and suggest a functional relationship between centromeres and nucleoli during interphase.

    • Barbara Mellone
    • Sylvia Erhardt
    • Gary H. Karpen
    News & Views
    Nature Cell Biology
    Volume: 8, P: 427-429