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Advanced filters: Author: Syrena Bracey Clear advanced filters

  • Pancreatic β-cells are naturally prone to ER stress due to their role in insulin production and secretion. Here, the authors show that chronic ER stress adaptive exhaustion results in an irreversible loss of β-cell function leading to T1D pathogenesis

    • Chien-Wen Chen
    • Bo-Jhih Guan
    • Maria Hatzoglou
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18