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Advanced filters: Author: Szu-Chieh Mei Clear advanced filters

YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis

YAP upregulates TET1, which physically interacts with TEAD1/4 to demethylate DNA at YAP target genes in the liver. Loss of TET1 reverses YAP-induced chromatin and transcriptional changes and suppresses YAP-induced hepatomegaly and tumorigenesis.

Bo-Kuan Wu
Szu-Chieh Mei
Duojia Pan
Research14 Jul 2022
Nature Genetics

Volume: 54, P: 1202-1213
Germ plasm localisation of the HELICc of Vasa in Drosophila: analysis of domain sufficiency and amino acids critical for localisation

Szu-Chieh Wang
Hao-Jen Hsu
Ming-Der Lin
ResearchOpen Access30 Sept 2015
Scientific Reports

Volume: 5, P: 1-16

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YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis

Germ plasm localisation of the HELICc of Vasa in Drosophila: analysis of domain sufficiency and amino acids critical for localisation

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