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Gene Therapy (4)
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Showing 1–7 of 7 results

Advanced filters: Author: T Dalkara Clear advanced filters

High levels of AAV vector integration into CRISPR-induced DNA breaks

In-depth characterization of adeno-associated virus (AAV)-mediated CRISPR delivery is still lacking. Here, the authors show high levels of integration into Cas9-induced double-strand breaks (DSBs) in therapeutically relevant genes in vivo.

Killian S. Hanlon
Benjamin P. Kleinstiver
Bence György
ResearchOpen Access30 Sept 2019
Nature Communications

Volume: 10, P: 1-11
Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina

D G Hickey
T L Edwards
R E MacLaren
ResearchOpen Access16 Nov 2017
Gene Therapy

Volume: 24, P: 787-800
Nitric oxide in health and disease of the nervous system

H-Y Yun
V L Dawson
T M Dawson
Reviews01 Jul 1997
Molecular Psychiatry

Volume: 2, P: 300-310
Reduced retinal transduction and enhanced transgene-directed immunogenicity with intravitreal delivery of rAAV following posterior vitrectomy in dogs

R F Boyd
S L Boye
J T Bartoe
Research07 Apr 2016
Gene Therapy

Volume: 23, P: 548-556
Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9

D Dalkara
L C Byrne
J G Flannery
Research20 Oct 2011
Gene Therapy

Volume: 19, P: 176-181
Intravenously administered propidium iodide labels necrotic cells in the intact mouse brain after injury

I Unal Cevik
T Dalkara
Correspondence17 Jul 2003
Cell Death & Differentiation

Volume: 10, P: 928-929
Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h−/− mouse

L C Byrne
B E Öztürk
J G Flannery
Research03 Apr 2014
Gene Therapy

Volume: 21, P: 585-592