As the prevalence of chronic kidney disease increases, new strategies to reverse or prevent tissue damage are under investigation. Here, Rabelink and Little describe progenitor cell populations that may have a key role in tissue repair and regeneration in the kidney. They also discuss the potential to harness the innate regenerative capacity of the kidney in the context of ongoing studies of mesenchymal stromal cell therapy.
- Ton J. Rabelink
- Melissa H. Little
