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Showing 1–50 of 91 results

Advanced filters: Author: T Kosaka Clear advanced filters

Tunable Dirac cone in the topological insulator Bi_2-xSb_xTe_3-ySe_y

The surface electronic structure of topological insulators is characterized by a so-called Dirac cone energy dispersion. This study shows that by tuning the compositions in the compound Bi_2−xSb_xTe_3−ySe_yone can control the precise features of its Dirac cone structure while keeping it a bulk insulator.

T. Arakane
T. Sato
Yoichi Ando
Research24 Jan 2012
Nature Communications

Volume: 3, P: 1-5
Hippocampal pyramidal cells excite inhibitory neurons through a single release site

A. I. Gulyás
R. Miles
T. F. Freund
Research16 Dec 1993
Nature

Volume: 366, P: 683-687
Detection of gastric cancer-associated microRNAs on microRNA microarray comparing pre- and post-operative plasma

H Konishi
D Ichikawa
E Otsuji
ResearchOpen Access19 Jan 2012
British Journal of Cancer

Volume: 106, P: 740-747
Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking

K Sugio
H Uramoto
K Yasumoto
ResearchOpen Access21 Mar 2006
British Journal of Cancer

Volume: 94, P: 896-903
Antitumour Properties of Phleomycin

W. T. BRADNER
M. H. PINDELL
Research17 Nov 1962
Nature

Volume: 196, P: 682-683
The important role for βVLDLs binding at the fourth cysteine of first ligand-binding domain in the low-density lipoprotein receptor

Tadao Iwasaki
Sadao Takahashi
Mitsuru Emi
Research01 Nov 2004
Journal of Human Genetics

Volume: 49, P: 622-628
A CPC-shelterin-BTR axis regulates mitotic telomere deprotection

Here the authors reveal how telomeres signal mitotic stress. A key protein network alters their structure exposing telomere ends to signal mitotic stress, ultimately triggering a controlled DNA damage response to remove faulty cells.

Diana Romero-Zamora
Samuel Rogers
Anthony J. Cesare
ResearchOpen Access17 Mar 2025
Nature Communications

Volume: 16, P: 1-19
The prognostic significance of vasohibin-1 expression in patients with prostate cancer

T Kosaka
Y Miyazaki
M Oya
ResearchOpen Access16 Apr 2013
British Journal of Cancer

Volume: 108, P: 2123-2129
Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma

M Sonobe
T Manabe
F Tanaka
ResearchOpen Access26 Jul 2005
British Journal of Cancer

Volume: 93, P: 355-363
Electrical conductivity of individual carbon nanotubes

T. W. Ebbesen
H. J. Lezec
T. Thio
Research04 Jul 1996
Nature

Volume: 382, P: 54-56
Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation

Miles A. Whittington
Roger D. Traub
John G. R. Jefferys
Research16 Feb 1995
Nature

Volume: 373, P: 612-615
Distinctive activation patterns in constitutively active and gefitinib-sensitive EGFR mutants

Y-R Chen
Y-N Fu
S-F Huang
Research03 Oct 2005
Oncogene

Volume: 25, P: 1205-1215
Predictive factors associated with prolonged survival in patients with advanced non-small-cell lung cancer (NSCLC) treated with gefitinib

M Satouchi
S Negoro
T Mitsudomi
ResearchOpen Access27 Mar 2007
British Journal of Cancer

Volume: 96, P: 1191-1196
In situ Fibre Composites from Poly(phenylene sulphide)/Thermotropic Liquid Crystalline Polymer Blends. Melting, Crystallization, and Phase Behavior

T G Gopakumar
S Ponrathnam
Alain Fradet
Research01 Nov 1997
Polymer Journal

Volume: 29, P: 884-888
Dementia with Lewy bodies — from scientific knowledge to clinical insights

Dementia with Lewy bodies (DLB) causes about one-tenth of all instances of dementia. This Review considers the substantial progress made in the basic and clinical research in DLB within the past few years, with discussion of the definition, pathology, genetics, prognosis, clinical features and current and future treatment of DLB.

Nikitas A. Arnaoutoglou
John T. O’Brien
Benjamin R. Underwood
Reviews17 Dec 2018
Nature Reviews Neurology

Volume: 15, P: 103-112
Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1

JN.1 lineage is a globally dominant variant of SARS-CoV-2. Here, the authors examine structural insights into the BA.2.86 and JN.1 spike dynamics to help understand the mechanisms underlying SARS-CoV-2 infection and its neutralizing-antibody evasion.

Hisano Yajima
Yuki Anraku
Takao Hashiguchi
ResearchOpen Access07 Oct 2024
Nature Communications

Volume: 15, P: 1-14
A design principle of polymers processable into 2D homeotropic order

Vertical alignment of polymers on surfaces is challenging due to their flexibility and tendency to arrange on horizontal planes. Here, the authors report a design principle allowing polymers to be arranged into 2D homeotropic orientations by using long-range dipole-dipole interactions and hot-pressing on Teflon sheets.

Zhen Chen
Yi-Tsu Chan
Takuzo Aida
ResearchOpen Access29 Nov 2016
Nature Communications

Volume: 7, P: 1-9
Unexpected mass acquisition of Dirac fermions at the quantum phase transition of a topological insulator

Time-reversal symmetry makes massless Dirac fermions in topological insulators ‘gapless’. When a gap opens, it breaks this symmetry and confers mass to the fermions. But now a quantum phase transition has been observed in a three-dimensional topological insulator that allows these particles to acquire mass without symmetry breaking.

T. Sato
Kouji Segawa
T. Takahashi
Research14 Aug 2011
Nature Physics

Volume: 7, P: 840-844
Protein-SIP enables time-resolved analysis of the carbon flux in a sulfate-reducing, benzene-degrading microbial consortium

Martin Taubert
Carsten Vogt
Jana Seifert
Research12 Jul 2012
The ISME Journal

Volume: 6, P: 2291-2301
Field programmable spin arrays for scalable quantum repeaters

Applications of solid-state qubits in large-scale quantum networks are limited by power and density constraints associated with microwave driving. Here the authors propose a programmable architecture based on diamond color centers driven by electric or strain fields for reduced cross-talk and power consumption.

Hanfeng Wang
Matthew E. Trusheim
Dirk R. Englund
ResearchOpen Access09 Feb 2023
Nature Communications

Volume: 14, P: 1-9
Ultra-high dynamic range quantum measurement retaining its sensitivity

Usually, quantum sensing protocols impose a trade-off between sensitivity and maximum range. Here, the authors demonstrate a non-adaptive algorithm for quantum sensors to measure AC fields with a large range for which the loss in sensitivity is negligible.

E. D. Herbschleb
H. Kato
N. Mizuochi
ResearchOpen Access12 Jan 2021
Nature Communications

Volume: 12, P: 1-8
Redox-responsive molecular helices with highly condensed π-clouds

Phenylene oligomers are shown to form left- and right-handed helices in solution, but a chiral symmetry-breaking process occurs on crystallization to give a non-racemic mixture of crystals that each contains only one enantiomer. One-electron oxidation of the oligomers suppresses the interconversion of the mirror-image helices in solution, locking-in one conformation and leading to chiral memory effects.

Eisuke Ohta
Hiroyasu Sato
Takuzo Aida
Research14 Nov 2010
Nature Chemistry

Volume: 3, P: 68-73
Angiotensin-2 receptors (AT1-R and AT2-R), new prognostic factors for renal clear-cell carcinoma?

T Dolley-Hitze
F Jouan
C Vigneau
ResearchOpen Access23 Nov 2010
British Journal of Cancer

Volume: 103, P: 1698-1705
Detection of the growth fraction in colorectal tumours by a monoclonal antibody against DNA polymerase α

A Yamaguchi
S Takegawa
I Miyazaki
Research01 Mar 1990
British Journal of Cancer

Volume: 61, P: 390-393
Constitutive production of multiple colony-stimulting factors in patients with lung cancer associated with neutrophilia

N Adachi
K Yamaguchi
K Abe
Research01 Jan 1994
British Journal of Cancer

Volume: 69, P: 125-129
Human chorionic gonadotropin in colorectal cancer and its relationship to prognosis

A Yamaguchi
T Ishida
I Miyazaki
Research01 Sept 1989
British Journal of Cancer

Volume: 60, P: 382-384
Enhanced electron-phonon coupling for a semiconductor charge qubit in a surface phonon cavity

J. C. H. Chen
Y. Sato
T. Fujisawa
ResearchOpen Access15 Oct 2015
Scientific Reports

Volume: 5, P: 1-8
Isolation of rare recombinants without using selectable markers for one-step seamless BAC mutagenesis

Application of the founder principle from population genetics to variant selection after recombineering allows the isolation of rare unselected recombinants.

George T Lyozin
Paul C Bressloff
Luca Brunelli
Research13 Jul 2014
Nature Methods

Volume: 11, P: 966-970
Association of PKC δ and active Src in PMA-treated MCF-7 human breast cancer cells

Malathy Shanmugam
Nancy L Krett
Mary Hunzicker-Dunn
Research23 Apr 1998
Oncogene

Volume: 16, P: 1649-1654
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA)

H Kimura
M Suminoe
S Nakao
ResearchOpen Access11 Sept 2007
British Journal of Cancer

Volume: 97, P: 778-784
Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors

T John
G Liu
M-S Tsao
Reviews14 Aug 2009
Oncogene

Volume: 28, P: S14-S23
EGFR mutation status in tumour-derived DNA from pleural effusion fluid is a practical basis for predicting the response to gefitinib

H Kimura
Y Fujiwara
K Nishio
ResearchOpen Access24 Oct 2006
British Journal of Cancer

Volume: 95, P: 1390-1395
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

It is unclear whether bidirectional non-coding RNAs transcribed from enhancer elements (eRNAs) have any functional role; here, the repressive functions of Rev-Erb nuclear receptors in macrophages are shown to be linked to their ability to inhibit the transcription of eRNAs.

Michael T. Y. Lam
Han Cho
Christopher K. Glass
Research02 Jun 2013
Nature

Volume: 498, P: 511-515
Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review

Bodhini et al. systematically review the evidence on sociodemographic, clinical, behavioral, and molecular factors that modify the effect of interventions for type 2 diabetes prevention. The certainty of evidence that such factors modify the effectiveness of lifestyle and behavioral interventions is low to very low.

Dhanasekaran Bodhini
Robert W. Morton
Ruth J. F. Loos
ResearchOpen Access05 Oct 2023
Communications Medicine

Volume: 3, P: 1-17
Prevalence and specificity of LKB1 genetic alterations in lung cancers

S Matsumoto
R Iwakawa
J Yokota
Research26 Mar 2007
Oncogene

Volume: 26, P: 5911-5918
Leukemia cell to endothelial cell communication via exosomal miRNAs

T Umezu
K Ohyashiki
J H Ohyashiki
Research16 Jul 2012
Oncogene

Volume: 32, P: 2747-2755
Mutation analysis of the ALD gene in seven Japanese families with X-linked adrenoleukodystrophy

T. Matsumoto
A. Tsuru
K. Tamagawa
Research01 Mar 2003
Journal of Human Genetics

Volume: 48, P: 125-129
Decreased expression of messenger RNAs encoding endothelin receptors and neutral endopeptidase 24.11 in endometrial cancer

F Pekonen
T Nyman
E-M Rutanen
Research01 Jan 1995
British Journal of Cancer

Volume: 71, P: 59-63
Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

Makoto Mitsunaga et al. have developed a new form of molecular-targeted cancer therapy that provides an alternative to current photodynamic approaches where damage to surrounding healthy cells and tissues can be a problem. They use a target-specific photosensitizer based on a near-infrared phthalocyanine dye, which is conjugated to monoclonal antibodies targeting human epidermal growth factor receptors (HER1 and HER2). Selective treatment using this approach was shown in vivo in subcutaneous cancer xenografts in mice.

Makoto Mitsunaga
Mikako Ogawa
Hisataka Kobayashi
Research06 Nov 2011
Nature Medicine

Volume: 17, P: 1685-1691
BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8⁺ T cells

Kyle A. Romine
Kevin MacPherson
Evan F. Lind
ResearchOpen Access21 Jan 2023
Leukemia

Volume: 37, P: 580-592
Acquired platinum resistance enhances tumour angiogenesis through angiotensin II type 1 receptor in bladder cancer

N Tanaka
A Miyajima
M Oya
ResearchOpen Access04 Oct 2011
British Journal of Cancer

Volume: 105, P: 1331-1337
Controlling malignant pericardial effusion by intrapericardial carboplatin administration in patients with primary non-small-cell lung cancer

T Moriya
Y Takiguchi
T Kuriyama
ResearchOpen Access05 Sept 2000
British Journal of Cancer

Volume: 83, P: 858-862
Expression of the hematopoietic stem cell antigen CD34 on blood and bone marrow monoclonal plasma cells from patients with multiple myeloma

T Kimlinger
TE Witzig
Research01 Mar 1997
Bone Marrow Transplantation

Volume: 19, P: 553-556
Induction of oesophageal and forestomach carcinomas in rats by reflux of duodenal contents

K Miwa
M Segawa
T Hattori
Research01 Aug 1994
British Journal of Cancer

Volume: 70, P: 185-189
Blood pressure, insulin, and haematocrit values in Japanese subjects over 60 years of age

T Yanagawa
Y Yoshida
T Saruta
Research01 Jun 1997
Journal of Human Hypertension

Volume: 11, P: 355-359
Circulating microRNAs in plasma of patients with oesophageal squamous cell carcinoma

S Komatsu
D Ichikawa
E Otsuji
ResearchOpen Access14 Jun 2011
British Journal of Cancer

Volume: 105, P: 104-111
Characterization of new polymorphisms in the 5′UTR of the human interleukin-1 receptor type 1 (IL1R1) gene: linkage to type 1 diabetes and correlation to IL-1RI plasma level

R Bergholdt
ZM Larsen
F Pociot
Research18 Dec 2000
Genes & Immunity

Volume: 1, P: 495-500
Role of plasma insulin concentration in regulating glucose and lipid metabolism in lean and obese Zucker rats

O Noshiro
R Hirayama
H Shikama
Research01 Feb 1997
International Journal of Obesity

Volume: 21, P: 115-121
Role of alpha 2 beta 1- and alpha 3 beta 1-integrin in the peritoneal implantation of scirrhous gastric carcinoma

S Nishimura
YS Chung
M Sowa
Research01 Nov 1996
British Journal of Cancer

Volume: 74, P: 1406-1412

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