Nature Search

GWAS for primary angle-closure glaucoma identifies loci related to ocular biometry and morphology

Primary angle-closure glaucoma can cause blindness. Here, the authors study populations of Asian and European ancestries and find that genetic factors associated with darker irises and being far sighted increase the risk of developing the condition.

Robert N. Luben
Mahantesh I. Biradar
Anthony P. Khawaja
ResearchOpen Access14 Nov 2025
Nature Communications

Volume: 16, P: 1-13
Functionally deficient UBOX5 variants and primary angle-closure glaucoma

Primary angle-closure glaucoma is a leading cause of blindness. Here, the authors identify rare deleterious variants in UBOX5 as risk factors and implicate BIP ubiquitination as a potential disease mechanism.

Zheng Li
Wee Ling Chng
Chiea Chuen Khor
ResearchOpen Access15 Aug 2025
Nature Communications

Volume: 16, P: 1-13
Batelli Glands of Cercopoid Nymphs (Homoptera)

A. T. MARSHALL
Research27 Feb 1965
Nature

Volume: 205, P: 925
Lrig1-expression confers suppressive function to CD4⁺ cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis

Regulatory T cells, and to certain extent other T cell subsets, limit the immune response to avoid harmful inflammation and tissue damage. Here authors identify a surface molecule, Lrig1, that is directly responsible for the suppressive function in regulatory T cells and in Il-17-producing helper T cells.

Jae-Seung Moon
Chun-Chang Ho
Sang-Kyou Lee
ResearchOpen Access04 Sept 2023
Nature Communications

Volume: 14, P: 1-16
Food intake, serum lipids and amino acids of school children in agricultural communities in Japan

T Fukushima
N Hojo
Y Yamane
Research05 Mar 1999
European Journal of Clinical Nutrition

Volume: 53, P: 207-210
Process insights for harnessing biotechnology for plastic depolymerization

Plastics play an essential role in modern life, but their uncontrolled disposal has led to severe environmental impacts. Sustainable strategies for reusing plastics waste are urgently needed. This Perspective examines biotechnological solutions for plastics recycling and upcycling, with an emphasis on the process-oriented challenges involved in achieving a circular plastics economy.

Ren Wei
Gert Weber
Uwe T. Bornscheuer
Reviews17 Feb 2025
Nature Chemical Engineering

Volume: 2, P: 110-117
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Chiea Chuen Khor, Tin Aung, Francesca Pasutto, Janey Wiggs and colleagues report a global genome-wide association study of exfoliation syndrome and a fine-mapping analysis of a previously identified disease-associated locus, LOXL1. They identify a rare protective variant in LOXL1 exclusive to the Japanese population and five new common variant susceptibility loci.

Tin Aung
Mineo Ozaki
Chiea Chuen Khor
Research29 May 2017
Nature Genetics

Volume: 49, P: 993-1004
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
The genome of the social amoeba Dictyostelium discoideum

L. Eichinger
J. A. Pachebat
A. Kuspa
Research05 May 2005
Nature

Volume: 435, P: 43-57
A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females

Girls are tenfold more likely than boys to require surgical treatment for idiopathic scoliosis, a common paediatric skeletal disorder. Here, Sharma et al. identify the first sexually dimorphic idiopathic scoliosis risk locus, and demonstrate that it may play a role in the regulation of spinal cells.

Swarkar Sharma
Douglas Londono
Carol A. Wise
ResearchOpen Access18 Mar 2015
Nature Communications

Volume: 6, P: 1-10
IκBζ regulates T_H17 development by cooperating with ROR nuclear receptors

Interleukin-17-producing helper T (T_H17) cells are a distinct T-cell subset characterized by its role in autoimmune disease. Here it is shown that the development of T_H17 cells requires the transcription factor IκBζ, as well as nuclear receptors of the ROR family. Mice lacking IκBζ have a defect in T_H17 development and are resistant to the induction of experimental autoimmune encephalomyelitis. The study points to some new potential molecular targets for drugs to treat autoimmune disease.

Kazuo Okamoto
Yoshiko Iwai
Hiroshi Takayanagi
Research01 Apr 2010
Nature

Volume: 464, P: 1381-1385
Noninvasive, epigenetic age estimation in an elasmobranch, the cownose ray (Rhinoptera bonasus)

D. Nick Weber
Jennifer T. Wyffels
David S. Portnoy
ResearchOpen Access01 Nov 2024
Scientific Reports

Volume: 14, P: 1-8
Diverting organic waste from landfills via insect biomanufacturing using engineered black soldier flies (Hermetia illucens)

This perspective describes how insects, such as Hermetia illucens, which are already used to process organic wastes at industrial scales, could be developed as a synthetic biology platform for sustainable biomanufacturing and bioremediation.

Kate Tepper
Owain Edwards
Maciej Maselko
ReviewsOpen Access24 Jul 2024
Communications Biology

Volume: 7, P: 1-14
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

Chiea Chuen Khor, Tin Aung and colleagues report the results of a large genome-wide association study of primary angle closure glaucoma. They identify five new susceptibility loci and provide insights into disease pathogenesis.

Chiea Chuen Khor
Tan Do
Tin Aung
Research04 Apr 2016
Nature Genetics

Volume: 48, P: 556-562
Potential routes of plastics biotransformation involving novel plastizymes revealed by global multi-omic analysis of plastic associated microbes

Rodney S. Ridley Jr
Roth E. Conrad
Konstantinos T. Konstantinidis
ResearchOpen Access16 Apr 2024
Scientific Reports

Volume: 14, P: 1-19
Tropical rhodolith beds are a major and belittled reef fish habitat

Rodrigo L. Moura
Maria L. Abieri
Alex C. Bastos
ResearchOpen Access12 Jan 2021
Scientific Reports

Volume: 11, P: 1-10
A new brilliantly blue-emitting luciferin-luciferase system from Orfelia fultoni and Keroplatinae (Diptera)

Vadim R. Viviani
Jaqueline R. Silva
Carl H. Johnson
ResearchOpen Access15 Jun 2020
Scientific Reports

Volume: 10, P: 1-15
Outcome of late surgical treatment in patients with incomplete paraplegia due to spinal degenerative diseases

Y Kasai
D Shi
A Uchida
Research09 Nov 2004
Spinal Cord

Volume: 43, P: 171-174
A prospective study of stomach cancer death in relation to green tea consumption in Japan

Y Hoshiyama
T Kawaguchi
T Yoshimura
ResearchOpen Access23 Jul 2002
British Journal of Cancer

Volume: 87, P: 309-313
Clinical implications of leptin and its potential humoral regulators in long-term low-calorie diet therapy for obese humans

T Miyawaki
H Masuzaki
K Nakao
Research25 Jun 2002
European Journal of Clinical Nutrition

Volume: 56, P: 593-600
Muscle mass and functional correlates of insulin sensitivity in lean young Indian men

U S Unni
G Ramakrishnan
A V Kurpad
Research27 May 2009
European Journal of Clinical Nutrition

Volume: 63, P: 1206-1212
Physical activity and body mass index in elderly Iranians in Sweden: a population-based study

A Koochek
S-E Johansson
K Sundquist
Research25 Jul 2007
European Journal of Clinical Nutrition

Volume: 62, P: 1326-1332
Characterisation of radioiodinated flavonoid derivatives for SPECT imaging of cerebral prion deposits

Takeshi Fuchigami
Yuki Yamashita
Morio Nakayama
ResearchOpen Access16 Dec 2015
Scientific Reports

Volume: 5, P: 1-11
Cord blood transplantation is associated with rapid B-cell neogenesis compared with BM transplantation

K Nakatani
K Imai
T Morio
Research30 Jun 2014
Bone Marrow Transplantation

Volume: 49, P: 1155-1161
Sample-efficient parameter exploration of the powder film drying process using experiment-based Bayesian optimization

Kohei Nagai
Takayuki Osa
Keisuke Nagato
ResearchOpen Access08 Feb 2022
Scientific Reports

Volume: 12, P: 1-11
An analysis of emerging food safety and fraud risks of novel insect proteins within complex supply chains

A. Traynor
D. Thorburn Burns
C. T. Elliott
ReviewsOpen Access20 Jan 2024
npj Science of Food

Volume: 8, P: 1-12
Agonist dependency of the second phase access of β-arrestin 2 to the heteromeric µ-V1b receptor

Nuttawadee Ngamlertwong
Hiroyoshi Tsuchiya
Taka-aki Koshimizu
ResearchOpen Access04 Aug 2021
Scientific Reports

Volume: 11, P: 1-13
The importance of antimicrobial resistance in medical mycology

The impact of fungal infections on human health has been exacerbated by the rise of antifungal drug resistance. In this Review, the authors outline the problem of antifungal resistance and suggest how this growing threat might be mitigated.

Neil A. R. Gow
Carolyn Johnson
Keegan Edgar
ReviewsOpen Access12 Sept 2022
Nature Communications

Volume: 13, P: 1-12
Hematopoietic stem cell transplantation for adults with EBV-positive T- or NK-cell lymphoproliferative disorders: efficacy and predictive markers

A Arai
C Sakashita
O Miura
Correspondence22 Feb 2016
Bone Marrow Transplantation

Volume: 51, P: 879-882
Rapid diagnosis of ataxia-telangiectasia by flow cytometric monitoring of DNA damage-dependent ATM phosphorylation

M Honda
M Takagi
S Mizuatni
Correspondence17 Jul 2008
Leukemia

Volume: 23, P: 409-414
Hematopoietic stem cell transplantation for 30 patients with primary immunodeficiency diseases: 20 years experience of a single team

Y Tsuji
K Imai
S Mizutani
Research23 Jan 2006
Bone Marrow Transplantation

Volume: 37, P: 469-477
Correction of immunodeficiency associated with NEMO mutation by umbilical cord blood transplantation using a reduced-intensity conditioning regimen

C Tono
Y Takahashi
E Ito
Correspondence09 Apr 2007
Bone Marrow Transplantation

Volume: 39, P: 801-804
A nested case–control study of stomach cancer in relation to green tea consumption in Japan

Y Hoshiyama
T Kawaguchi
T Yoshimura
ResearchOpen Access06 Jan 2004
British Journal of Cancer

Volume: 90, P: 135-138
Insufficient immune reconstitution after allogeneic cord blood transplantation without chemotherapy conditioning in patients with SCID caused by CD3δ deficiency

H Takada
M Ishimura
T Hara
Correspondence21 Mar 2016
Bone Marrow Transplantation

Volume: 51, P: 1131-1133
DNA damage check points prevent leukemic transformation in myelodysplastic syndrome

S Horibe
M Takagi
S Mizutani
Correspondence10 May 2007
Leukemia

Volume: 21, P: 2195-2198

Search

GWAS for primary angle-closure glaucoma identifies loci related to ocular biometry and morphology

Functionally deficient UBOX5 variants and primary angle-closure glaucoma

Batelli Glands of Cercopoid Nymphs (Homoptera)

Lrig1-expression confers suppressive function to CD4⁺ cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis

Food intake, serum lipids and amino acids of school children in agricultural communities in Japan

Process insights for harnessing biotechnology for plastic depolymerization

Mapping the human genetic architecture of COVID-19

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

A second update on mapping the human genetic architecture of COVID-19

The genome of the social amoeba Dictyostelium discoideum

A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females

IκBζ regulates T_H17 development by cooperating with ROR nuclear receptors

Noninvasive, epigenetic age estimation in an elasmobranch, the cownose ray (Rhinoptera bonasus)

Diverting organic waste from landfills via insect biomanufacturing using engineered black soldier flies (Hermetia illucens)

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

Potential routes of plastics biotransformation involving novel plastizymes revealed by global multi-omic analysis of plastic associated microbes

Tropical rhodolith beds are a major and belittled reef fish habitat

A new brilliantly blue-emitting luciferin-luciferase system from Orfelia fultoni and Keroplatinae (Diptera)

Outcome of late surgical treatment in patients with incomplete paraplegia due to spinal degenerative diseases

A prospective study of stomach cancer death in relation to green tea consumption in Japan

Clinical implications of leptin and its potential humoral regulators in long-term low-calorie diet therapy for obese humans

Muscle mass and functional correlates of insulin sensitivity in lean young Indian men

Physical activity and body mass index in elderly Iranians in Sweden: a population-based study

Characterisation of radioiodinated flavonoid derivatives for SPECT imaging of cerebral prion deposits

Cord blood transplantation is associated with rapid B-cell neogenesis compared with BM transplantation

Sample-efficient parameter exploration of the powder film drying process using experiment-based Bayesian optimization

An analysis of emerging food safety and fraud risks of novel insect proteins within complex supply chains

Agonist dependency of the second phase access of β-arrestin 2 to the heteromeric µ-V1b receptor

The importance of antimicrobial resistance in medical mycology

Hematopoietic stem cell transplantation for adults with EBV-positive T- or NK-cell lymphoproliferative disorders: efficacy and predictive markers

Rapid diagnosis of ataxia-telangiectasia by flow cytometric monitoring of DNA damage-dependent ATM phosphorylation

Hematopoietic stem cell transplantation for 30 patients with primary immunodeficiency diseases: 20 years experience of a single team

Correction of immunodeficiency associated with NEMO mutation by umbilical cord blood transplantation using a reduced-intensity conditioning regimen

A nested case–control study of stomach cancer in relation to green tea consumption in Japan

Insufficient immune reconstitution after allogeneic cord blood transplantation without chemotherapy conditioning in patients with SCID caused by CD3δ deficiency

DNA damage check points prevent leukemic transformation in myelodysplastic syndrome

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