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Showing 1–50 of 72 results

Advanced filters: Author: T Taga Clear advanced filters

DNA recognition by β-sheets in the Arc represser–operator crystal structure

Brigitte E. Raumann
Mark A. Rould
Robert T. Sauer
Research24 Feb 1994
Nature

Volume: 367, P: 754-757
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design

Non-canonical amino acids can be incorporated into proteins through translation of orthogonal mRNAs. Now, automating the design of orthogonal mRNAs—which are more selectively and efficiently translated—in combination with compact orthogonal aminoacyl-tRNA synthetase/tRNA expression systems, enables the incorporation of four distinct non-canonical monomers via a 68-codon genetic code.

Daniel L. Dunkelmann
Sebastian B. Oehm
Jason W. Chin
Research23 Aug 2021
Nature Chemistry

Volume: 13, P: 1110-1117
Dramatic changes in DNA-binding specificity caused by single residue substitutions in an Arc/Mnt hybrid repressor

Brigitte E. Raumann
Kendall L. Knight
Robert T. Sauer
Research01 Dec 1995
Nature Structural Biology

Volume: 2, P: 1115-1122
p16 protein expression is associated with a poor prognosis in squamous cell carcinoma of the lung

C-I Huang
T Taki
M Miyake
ResearchOpen Access17 Dec 1999
British Journal of Cancer

Volume: 82, P: 374-380
Spectrum of antibacterial activity and mode of action of a novel tris-stilbene bacteriostatic compound

Nikki Y. T. Man
Daniel R. Knight
Katherine A. Hammer
ResearchOpen Access02 May 2018
Scientific Reports

Volume: 8, P: 1-9
Predictive value of expression of p16^INK4A, retinoblastoma and p53 proteins for the prognosis of non-small-cell lung cancers

F Hommura
H Dosaka-Akita
Y Kawakami
ResearchOpen Access24 Sept 1999
British Journal of Cancer

Volume: 81, P: 696-701
Effect of Anions on the Volume of Smooth Muscle

A. F. BRADING
T. TOMITA
Research20 Apr 1968
Nature

Volume: 218, P: 276-277
Interleukin-11 (IL-11) enhances clonal proliferation of acute myelogenous leukemia cells with strong expression of the IL-11 receptor α chain and signal transducing gp130

T Kimura
H Sakabe
Y Sonoda
Research22 Jul 1999
Leukemia

Volume: 13, P: 1018-1027
A recombination hotspot responsible for two inherited peripheral neuropathies is located near a mariner transposon-like element

Lawrence T. Reiter
Tatsufumi Murakami
James R. Lupski
Research01 Mar 1996
Nature Genetics

Volume: 12, P: 288-297
The genome of the social amoeba Dictyostelium discoideum

L. Eichinger
J. A. Pachebat
A. Kuspa
Research05 May 2005
Nature

Volume: 435, P: 43-57
Expression of interleukin 10 in human melanoma

S Krüger-Krasagakes
K Krasagakis
T Diamantstein
Research01 Dec 1994
British Journal of Cancer

Volume: 70, P: 1182-1185
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

Bruce A. Witthuhn
Olli Silvennoinen
James N. Ihle
Research14 Jul 1994
Nature

Volume: 370, P: 153-157
Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system

Microorganisms from the terrestrial subsurface are understudied. Here, Anantharamanet al. analyse aquifer sediments and groundwater by genome-resolved metagenomics and reconstruct 2,540 genomes representing the majority of known bacterial phyla as well as 47 new phylum-level lineages.

Karthik Anantharaman
Christopher T. Brown
Jillian F. Banfield
ResearchOpen Access24 Oct 2016
Nature Communications

Volume: 7, P: 1-11
Enhancement of the dielectric constant of Ta₂O₅through substitution with TiO₂

R. F. Cava
W. F. Peck Jr
J. J. Krajewski
Research21 Sept 1995
Nature

Volume: 377, P: 215-217
A subset of viruses thrives following microbial resuscitation during rewetting of a seasonally dry California grassland soil

Rewetting of seasonally dry soils induces dramatic shifts in viral biomass and diversity. Combining stable isotope probing, metagenomics, and viromics Nicolas et al. provide evidence that viral lysis contributes to microbial turnover and the associated CO₂ efflux.

Alexa M. Nicolas
Ella T. Sieradzki
Steven J. Blazewicz
ResearchOpen Access20 Sept 2023
Nature Communications

Volume: 14, P: 1-16
Transposition of a tandem duplication of yeast mating-type genes

James E. Haber
David T. Rogers
Research22 Apr 1982
Nature

Volume: 296, P: 768-770
Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira

L. G. V. Fernandes
L. P. Guaman
A. L. T. O. Nascimento
ResearchOpen Access12 Feb 2019
Scientific Reports

Volume: 9, P: 1-14
INPP5D regulates inflammasome activation in human microglia

INPP5D/SHIP1 is a microglial-expressed gene that has been associated with Alzheimer’s disease through genetic studies. This study reveals that reduction in INPP5D activity induces activation of the NLRP3-inflammasome in human microglia.

Vicky Chou
Richard V. Pearse II
Tracy L. Young-Pearse
ResearchOpen Access29 Nov 2023
Nature Communications

Volume: 14, P: 1-23
Thrombopoietin augments ex vivo expansion of human cord blood-derived hematopoietic progenitors in combination with stem cell factor and flt3 ligand

Y Ohmizono
H Sakabe
Y Sonoda
Research01 Apr 1997
Leukemia

Volume: 11, P: 524-530
Tiam1/Rac1 complex controls Il17a transcription and autoimmunity

Tiam1 is a guanine nucleotide exchange factor for the Rho-family GTPase Rac1. Here, the authors show that nuclear Tiam1 and Rac1 bind to RORγt on the IL-17 promoter, activating its transcription, and that inhibiting Tiam1/Rac1 is beneficial in a mouse model of autoimmunity.

Ahmed T. Kurdi
Ribal Bassil
Wassim Elyaman
ResearchOpen Access11 Oct 2016
Nature Communications

Volume: 7, P: 1-14
Mechanism of spreading of the highly related neurofibromatosis type 1 (NF1) pseudogenes on chromosomes 2, 14 and 22

Mirjam Luijten
YingPing Wang
Theo JM Hulsebos
Research17 May 2000
European Journal of Human Genetics

Volume: 8, P: 209-214
Interleukin 6 and its relationship to clinical parameters in patients with malignant pleural mesothelioma

T Nakano
AP Chahinian
K Higashino
Research01 Mar 1998
British Journal of Cancer

Volume: 77, P: 907-912
Vitamin interdependencies predicted by metagenomics-informed network analyses and validated in microbial community microcosms

Metagenomic data and network analyses are often used to predict microbial interactions in complex communities, but these predictions are rarely explored experimentally. Here, Hessler et al. combine experiments with metagenome-informed, microbial consortia-based network analyses to identify interactions in microbial consortia grown under dozens of conditions.

Tomas Hessler
Robert J. Huddy
Jillian F. Banfield
ResearchOpen Access08 Aug 2023
Nature Communications

Volume: 14, P: 1-12
Measurement of the inelastic proton–proton cross-section at √s=7 TeV with the ATLAS detector

The measurement of the total cross-section of proton–proton collisions is of fundamental importance for particle physics. Here, the first measurement of the inelastic cross-section is presented for proton–proton collisions at an energy of 7 teraelectronvolts using the ATLAS detector at the Large Hadron Collider.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access06 Sept 2011
Nature Communications

Volume: 2, P: 1-14
BluB cannibalizes flavin to form the lower ligand of vitamin B₁₂

The X-ray crystal structure of BluB is solved. Blub is an enzyme that uses molecular oxygen to cleave a flavin mononucleotide cofactor to form 5,6-dimethylbenzimidazole, which is incorporated into vitamin B₁₂. The enzymatic destruction of one cofactor to synthesis another is quite unusual and this biochemical reaction represents the last unknown step in the biosynthesis of this vitamin.

Michiko E. Taga
Nicholas A. Larsen
Graham C. Walker
Research22 Mar 2007
Nature

Volume: 446, P: 449-453
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

The authors constructed and validated a molecular network of the aging human cortex from RNA sequencing data from 478 individuals and identified genes that affect cognitive decline or neuropathology in Alzheimer’s disease.

Sara Mostafavi
Chris Gaiteri
Philip L. De Jager
Research25 May 2018
Nature Neuroscience

Volume: 21, P: 811-819
NEUROTOXICITY IN LEUKEMIC CHILDREN RECEIVING PROPHYLACTIC CRANIAL IRRADIATION AND MAINTENANCE HIGH DOSE METHOTREXATE

S Meintosh
G T Aspnes
H A Pearson
Research01 Apr 1974
Pediatric Research

Volume: 8, P: 405
The corrinoid cofactor of reductive dehalogenases affects dechlorination rates and extents in organohalide-respiring Dehalococcoides mccartyi

Jun Yan
Burcu Şimşir
Frank E Löffler
Research10 Nov 2015
The ISME Journal

Volume: 10, P: 1092-1101
The EuroChimerism concept for a standardized approach to chimerism analysis after allogeneic stem cell transplantation

T Lion
F Watzinger
P Bader
Research07 Mar 2012
Leukemia

Volume: 26, P: 1821-1828
Structure and function of a new STAT-induced STAT inhibitor

Tetsuji Naka
Masashi Narazaki
Tadamitsu Kishimoto
Research26 Jun 1997
Nature

Volume: 387, P: 924-929
Administration of G-CSF to normal individuals diminishes L-selectin⁺ T cells in the peripheral blood that respond better to alloantigen stimulation than L-selectin⁻ T cells

N Sugimori
S Nakao
Tamotsu Matsuda
Research01 Feb 1999
Bone Marrow Transplantation

Volume: 23, P: 119-124
Genome analysis of a halophilic bacterium Halomonas malpeensis YU-PRIM-29^T reveals its exopolysaccharide and pigment producing capabilities

Athmika
Sudeep D. Ghate
P. D. Rekha
ResearchOpen Access18 Jan 2021
Scientific Reports

Volume: 11, P: 1-14
Soluble interleukin-2 receptor, intercellular adhesion molecule-1 and interleukin-10 serum levels in patients with melanoma

M D Boyano
M D Garcia-Vázquez
J L Díaz-Pérez
ResearchOpen Access05 Sept 2000
British Journal of Cancer

Volume: 83, P: 847-852
Scalable characterization of the PAM requirements of CRISPR–Cas enzymes using HT-PAMDA

The high-throughput PAM determination assay (HT-PAMDA) described here enables scalable characterization of the PAM preferences of Cas proteins.

Russell T. Walton
Jonathan Y. Hsu
Benjamin P. Kleinstiver
Protocols05 Feb 2021
Nature Protocols

Volume: 16, P: 1511-1547
549 SELECTIVE FETAL MALNUTRITION: A NEW CONCEPT IN THE FETAL ALCOHOL SYNDROME (FAS)

Stanley E Fisher
Mark Atkinson
T K Oliver
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 532
p21 provides stage specific DNA damage control to preimplantation embryos

S K Adiga
M Toyoshima
O Niwa
Research09 Apr 2007
Oncogene

Volume: 26, P: 6141-6149
Serum hepatocyte growth factor as an index of disease status of patients with colorectal carcinoma

T Fukuura
C Miki
H Suzuki
Research01 Aug 1998
British Journal of Cancer

Volume: 78, P: 454-459
A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density

N. Ota
T. Nakajima
M. Emi
Research01 Apr 2001
Journal of Human Genetics

Volume: 46, P: 267-272
Serum levels of interleukin 6 in patients with lung cancer

H Yanagawa
S Sone
T Ogura
Research01 May 1995
British Journal of Cancer

Volume: 71, P: 1095-1098
Interleukin-6 cDNA transfected Lewis lung carcinoma cells show unaltered net tumour growth rate but cause weight loss and shortened survival in syngeneic mice

Y Ohe
ER Podack
N Saijo
Research01 May 1993
British Journal of Cancer

Volume: 67, P: 939-944
Allelic variants in the interleukin-6 gene and essential hypertension in Japanese women

T Nakajima
N Ota
M Emi
Research03 Nov 1999
Genes & Immunity

Volume: 1, P: 115-119
Glycogen synthase kinase-3β gene is associated with antidepressant treatment response in Chinese major depressive disorder

S-J Tsai
Y-J Liou
T-J Chen
Research15 Jan 2008
The Pharmacogenomics Journal

Volume: 8, P: 384-390
Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas

H. Nagai
T. Naka
M. Emi
Research01 Feb 2003
Journal of Human Genetics

Volume: 48, P: 65-69
The secondary resistome of multidrug-resistant Klebsiella pneumoniae

Bimal Jana
Amy K. Cain
Luca Guardabassi
ResearchOpen Access15 Feb 2017
Scientific Reports

Volume: 7, P: 1-10
Detection of methylthioadenosine phosphorylase (MTAP) and p16 gene deletion in T cell acute lymphoblastic leukemia by real-time quantitative PCR assay

TJ M'soka
J Nishioka
T Nobori
Research28 Apr 2000
Leukemia

Volume: 14, P: 935-940
Synthesis and Characterization of Hyperbranched Polymer Having Hole Transporting Ability

Jaekook Ha
Hee Cheong Lee
Hisaya Sato
Research15 Mar 2004
Polymer Journal

Volume: 36, P: 219-225
Identification of a 170-kDa protein over-expressed in lung cancers

R Pincheira
Q Chen
J-T Zhang
ResearchOpen Access29 May 2001
British Journal of Cancer

Volume: 84, P: 1520-1527
Autocrine IL-2-dependent growth of a newly established CD3⁺, CD16⁻, CD56⁺, CD57⁺, J_H⁻, TCRβ⁻, TCRγ⁻ leukemia cell line (NOI-90)

Y Sahraoui
M Perraki
V Georgoulias
Research01 Feb 1997
Leukemia

Volume: 11, P: 245-252
The role of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 regulator of transcription activation (RTA) in control of gene expression

John T West
Charles Wood
Reviews11 Aug 2003
Oncogene

Volume: 22, P: 5150-5163
In vitro excess ammonia production in human myeloma cell lines

T Otsuki
O Yamada
A Ueki
Research24 Jul 1998
Leukemia

Volume: 12, P: 1149-1158

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