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  • Targeted nanoparticle delivery to sites of interest is important for targeted therapeutics. Here, the authors improve the targeting efficiency of antibodies on nanoparticles using a monobody adapter to correctly orientate the antibody to preserve targeting function and demonstrate application in targeting the vascular endothelium of human kidneys.

    • C. Albert
    • L. Bracaglia
    • G. T. Tietjen
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • OrganEx—an extracorporeal pulsatile-perfusion system with cytoprotective perfusate for porcine whole-body settings—preserved tissue integrity, decreased cell death and restored selected molecular and cellular processes across multiple vital organs after 1 h of warm ischaemia in pigs.

    • David Andrijevic
    • Zvonimir Vrselja
    • Nenad Sestan
    Research
    Nature
    Volume: 608, P: 405-412