Tohru Minamino and Issei Komuro examine the research on age-associated vascular pathophysiology at the cellular level, specifically telomere shortening, DNA damage and the replicative ability of cardiovascular cells, particularly stem cells or progenitor cells. They explore vascular senescence in the context of human progeroid syndromes and what the future holds for the treatment of age-associated vascular disease.
- Tohru Minamino
- Issei Komuro