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Showing 1–6 of 6 results
Advanced filters: Author: T. T. Huyen Tu Clear advanced filters

  • Primary angle-closure glaucoma is a leading cause of blindness. Here, the authors identify rare deleterious variants in UBOX5 as risk factors and implicate BIP ubiquitination as a potential disease mechanism.

    • Zheng Li
    • Wee Ling Chng
    • Chiea Chuen Khor
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

    • Y. Umezaki
    • T. Naito
    • A. Toyofuku
    Research
    British Dental Journal
    Volume: 237, P: 73

  • The beetle Tribolium castaneum is a commonly used laboratory model, combining the ease of systematic RNAi experiments like those in Caenorhabditis elegans, with biology that is more representative of most insects than Drosophila melanogaster. A large consortium has sequenced and analysed the genome of the red flour beetle, creating a resource for biologists everywhere.

    • Stephen Richards
    • Richard A. Gibbs
    • Gregor Bucher
    ResearchOpen Access
    Nature
    Volume: 452, P: 949-955

  • The bed bug, Cimex lectularius, is a ubiquitous human ectoparasite with global distribution. Here, the authors sequence the genome of the bed bug and identify reductions in chemosensory genes, expansion of genes associated with blood digestion and genes linked to pesticide resistance.

    • Joshua B. Benoit
    • Zach N. Adelman
    • Stephen Richards
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-10

  • The goal of the 1000 Genomes Project is to provide in-depth information on variation in human genome sequences. In the pilot phase reported here, different strategies for genome-wide sequencing, using high-throughput sequencing platforms, were developed and compared. The resulting data set includes more than 95% of the currently accessible variants found in any individual, and can be used to inform association and functional studies.

    • Richard M. Durbin
    • David Altshuler (Co-Chair)
    • Gil A. McVean
    ResearchOpen Access
    Nature
    Volume: 467, P: 1061-1073