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Showing 1–5 of 5 results
Advanced filters: Author: Tadataka Tsuji Clear advanced filters

  • Thermogenic induction of white adipose tissue has the potential to prevent or treat obesity and its related complications. Here, the authors show that EDN3/EDNRB signaling induces the thermogenic differentiation of white adipose progenitor cells and promotes glucose and energy homeostasis.

    • Chih-Hao Wang
    • Tadataka Tsuji
    • Yu-Hua Tseng
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • Light is essential for biological life. Here, the authors show blue light activates the photoreceptor Opsin3 in white fat, triggering a light-responsive metabolic circuit involving adipose-hypothalamus communication, which could potentially alleviate obesity-induced metabolic abnormalities.

    • Tadataka Tsuji
    • Vladimir Tolstikov
    • Yu-Hua Tseng
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19

  • N6 - methyladenosine (m6 A) is a prevalent and abundant mRNA modification, yet its cell-type specific roles remains unclear. Here, the authors show that m6 A modification differentially regulates the transcriptomes of brown and white adipose tissue, resulting in distinct impacts on systemic metabolism.

    • Ling Xiao
    • Dario F. De Jesus
    • Rohit N. Kulkarni
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19