Lupus nephritis is a severe manifestation of systemic lupus erythematosus and a major cause of both acute kidney injury and end-stage renal disease. Preventing, or delaying progression of lupus nephritis is the primary objective of treatment. New treatments, or treatment regimens have substantially improved the overall prognosis of patients with lupus nephritis over the past 30 years. Here, Tak Mao Chan provides a detailed summary of the clinical efficacy of current treatment approaches, and the potential roles of emerging treatments for lupus nephritis.
