The enzyme Elovl6 catalyses a rate-limiting step in the elongation of fatty acids. Here Sunaga et al. show that Elovl6 knockout mice are more susceptible to pulmonary fibrosis, suggesting that the dysregulation of lipid components impairs alveolar epithelial cell function and pulmonary homeostasis.
- Hiroaki Sunaga
- Hiroki Matsui
- Masahiko Kurabayashi
