The first chemical synthesis of solanoeclepin A is described. The novel 5-4-6-7-5-5 polycyclic architecture was constructed in a stereoselective manner via a cyclopentene annulation strategy, the intramolecular cyclization of an epoxy nitrile intermediate, and an intramolecular Diels–Alder reaction of a furan derivative.
- Keiji Tanino
- Motomasa Takahashi
- Masaaki Miyashita
