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Showing 1–6 of 6 results
Advanced filters: Author: Takeaki Sugimura Clear advanced filters

  • Antiplatelet therapy is vital for coronary artery disease (CAD) management but hard to monitor effectively. Here, the authors show that comprehensive image-based profiling of circulating platelets can directly assess therapy efficacy and guide personalized treatment for CAD.

    • Kazutoshi Hirose
    • Satoshi Kodera
    • Keisuke Goda
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12

  • High throughput imaging flow cytometry suffers from trade-offs between throughput, sensitivity and spatial resolution. Here the authors introduce a method to virtually freeze cells in the image acquisition window to enable 1000 times longer signal integration time and improve signal-to-noise ratio.

    • Hideharu Mikami
    • Makoto Kawaguchi
    • Keisuke Goda
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • Most current cell sorting methods are based on fluorescence detection with no imaging capability. Here the authors generate and use Raman image-activated cell sorting with a throughput of around 100 events per second, providing molecular images with no need for labeling.

    • Nao Nitta
    • Takanori Iino
    • Keisuke Goda
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • A protocol for the design, construction, and operation of an intelligent image-activated cell sorting (iIACS) machine that performs real-time image-based sorting of single cells from heterogeneous populations with high throughput and intelligence.

    • Akihiro Isozaki
    • Hideharu Mikami
    • Keisuke Goda
    Protocols
    Nature Protocols
    Volume: 14, P: 2370-2415

  • This protocol describes how to build an optical time-stretch microscope and a cell-focusing microfluidic device for high-throughput (>10,000 cells per s) single-cell imaging by optofluidic time-stretch microscopy.

    • Cheng Lei
    • Hirofumi Kobayashi
    • Keisuke Goda
    Protocols
    Nature Protocols
    Volume: 13, P: 1603-1631