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CD8-positive T cells and CD204-positive M2-like macrophages predict postoperative prognosis of very high-risk prostate cancer

Yoshinori Yanai
Takeo Kosaka
Mototsugu Oya
ResearchOpen Access18 Nov 2021
Scientific Reports

Volume: 11, P: 1-7
Author Correction: MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer

Yota Yasumizu
Hasan Rajabi
Donald Kufe
Amendments and CorrectionsOpen Access24 Feb 2020
Nature Communications

Volume: 11, P: 1
Utility of prophylactic antibiotics for preventing febrile neutropenia during cabazitaxel therapy for castration-resistant prostate cancer

Keitaro Watanabe
Takeo Kosaka
Mototsugu Oya
ResearchOpen Access16 Apr 2021
Scientific Reports

Volume: 11, P: 1-7
MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer

MUC1-C is overexpressed in castration-resistant prostate cancer and neuroendocrine prostate cancer. Here, the authors show that MUC1-C drives lineage plasticity through MYC and BRN2, inducing neuroendocrine features and stemness in prostate cancer.

Yota Yasumizu
Hasan Rajabi
Donald Kufe
ResearchOpen Access17 Jan 2020
Nature Communications

Volume: 11, P: 1-13
Subtype-specific collaborative transcription factor networks are promoted by OCT4 in the progression of prostate cancer

Transcription factors (TFs) often form distinct networks to regulate transcriptional program during cancer progression. Here the authors show that OCT4 is a common transcriptional factor in two types of advanced PC and as such, OCT4 accelerates a TF complex formation with the FOXA1/AR in castration-resistant PC and NRF1 in neuroendocrine PC.

Ken-ichi Takayama
Takeo Kosaka
Satoshi Inoue
ResearchOpen Access18 Jun 2021
Nature Communications

Volume: 12, P: 1-16
Prediction of extraprostatic extension by MRI tumor contact length: difference between anterior and posterior prostate cancer

Kazuhiro Matsumoto
Hirotaka Akita
Masahiro Jinzaki
Research27 Feb 2019
Prostate Cancer and Prostatic Diseases

Volume: 22, P: 539-545
Human castration resistant prostate cancer rather prefer to decreased 5α-reductase activity

Takeo Kosaka
Akira Miyajima
Mototsugu Oya
ResearchOpen Access14 Feb 2013
Scientific Reports

Volume: 3, P: 1-6
Dinuclear Cu(I) molecular electrocatalyst for CO₂-to-C₃ product conversion

The tunable design of molecular catalysts presents opportunities for the control of product selectivity in CO₂ reduction, yet to date, complexes capable of producing multicarbon products have been elusive. Here, a Br-bridged dinuclear Cu(I) complex that turns over C₃H₇OH is reported.

Naonari Sakamoto
Keita Sekizawa
Takeshi Morikawa
ResearchOpen Access15 Apr 2024
Nature Catalysis

Volume: 7, P: 574-584
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Topoisomerase II alpha inhibition can overcome taxane-resistant prostate cancer through DNA repair pathways

Hiroshi Hongo
Takeo Kosaka
Mototsugu Oya
ResearchOpen Access15 Nov 2021
Scientific Reports

Volume: 11, P: 1-10
Discovery of a new candidate drug to overcome cabazitaxel-resistant gene signature in castration-resistant prostate cancer by in silico screening

Hiroshi Hongo
Takeo Kosaka
Mototsugu Oya
ResearchOpen Access30 Sept 2021
Prostate Cancer and Prostatic Diseases

Volume: 26, P: 59-66
Increased vasohibin-1 expression is associated with metastasis and poor prognosis of renal cell carcinoma patients

Shuji Mikami
Mototsugu Oya
Yasunori Okada
Research13 Mar 2017
Laboratory Investigation

Volume: 97, P: 854-862
MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells

Tatsuaki Daimon
Atrayee Bhattacharya
Donald W. Kufe
ResearchOpen Access05 Jan 2024
Cell Death Discovery

Volume: 10, P: 1-14
Hybridisation chain reaction-based visualisation and screening for lncRNA profiles in clear-cell renal-cell carcinoma

Ryohei Kufukihara
Nobuyuki Tanaka
Mototsugu Oya
Research28 Jun 2022
British Journal of Cancer

Volume: 127, P: 1133-1141
A commentary on Helicobacter pylori and gastric cancer risk in BRCA1/2 pathogenic germline variant carrier

Hiroyuki Matsubayashi
Takeo Kosaka
Arisa Ueki
Comments & Opinion06 Jul 2023
Journal of Human Genetics

Volume: 68, P: 727-728
Clinical risk management of breast, ovarian, pancreatic, and prostatic cancers for BRCA1/2 variant carriers in Japan

Arisa Ueki
Reiko Yoshida
Hiroyuki Matsubayashi
Reviews24 Apr 2023
Journal of Human Genetics

Volume: 68, P: 517-526
TNFAIP2 expression induces epithelial-to-mesenchymal transition and confers platinum resistance in urothelial cancer cells

Naoya Niwa
Nobuyuki Tanaka
Mototsugu Oya
Research01 Jul 2019
Laboratory Investigation

Volume: 99, P: 1702-1713
Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis

Shuji Mikami
Ken-Ichi Katsube
Yasunori Okada
Research01 Aug 2011
Laboratory Investigation

Volume: 91, P: 1443-1458

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CD8-positive T cells and CD204-positive M2-like macrophages predict postoperative prognosis of very high-risk prostate cancer

Author Correction: MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer

Utility of prophylactic antibiotics for preventing febrile neutropenia during cabazitaxel therapy for castration-resistant prostate cancer

MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer

Subtype-specific collaborative transcription factor networks are promoted by OCT4 in the progression of prostate cancer

Prediction of extraprostatic extension by MRI tumor contact length: difference between anterior and posterior prostate cancer

Human castration resistant prostate cancer rather prefer to decreased 5α-reductase activity

Dinuclear Cu(I) molecular electrocatalyst for CO₂-to-C₃ product conversion

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Topoisomerase II alpha inhibition can overcome taxane-resistant prostate cancer through DNA repair pathways

Discovery of a new candidate drug to overcome cabazitaxel-resistant gene signature in castration-resistant prostate cancer by in silico screening

Increased vasohibin-1 expression is associated with metastasis and poor prognosis of renal cell carcinoma patients

MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells

Hybridisation chain reaction-based visualisation and screening for lncRNA profiles in clear-cell renal-cell carcinoma

A commentary on Helicobacter pylori and gastric cancer risk in BRCA1/2 pathogenic germline variant carrier

Clinical risk management of breast, ovarian, pancreatic, and prostatic cancers for BRCA1/2 variant carriers in Japan

TNFAIP2 expression induces epithelial-to-mesenchymal transition and confers platinum resistance in urothelial cancer cells

Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis

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