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Advanced filters: Author: Tali E. Haran Clear advanced filters

DNA mismatches reveal conformational penalties in protein–DNA recognition

A high-throughput assay that introduces mismatched base pairs into the DNA sequence shows that mismatches can increase transcription factor binding affinity by prepaying some of the energetic cost of distorting the DNA.

Ariel Afek
Honglue Shi
Raluca Gordân
Research21 Oct 2020
Nature

Volume: 587, P: 291-296
DNA binding and 3′–5′ exonuclease activity in the murine alternatively-spliced p53 protein

Zippora Shakked
Michael Yavnilovitch
Tali E Haran
Research29 Jul 2002
Oncogene

Volume: 21, P: 5117-5126
Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog

Qiang Zhang
Dimitrios-Ilias Balourdas
Andreas C. Joerger
ResearchOpen Access07 Mar 2022
Cell Death & Disease

Volume: 13, P: 1-11