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Advanced filters: Author: Tania Baccega Clear advanced filters

  • A strategy developed to define off-target effects of gene-editing nucleases in whole organisms is validated and leveraged to show that CRISPR–Cas9 nucleases can be used effectively in vivo without inducing detectable off-target mutations.

    • Pinar Akcakaya
    • Maggie L. Bobbin
    • J. Keith Joung
    Research
    Nature
    Volume: 561, P: 416-419