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Showing 1–19 of 19 results
Advanced filters: Author: Tanja Stadler Clear advanced filters

  • The relative importance of close-proximity interactions, shared space and air quality to the transmission of respiratory viruses is not well understood. Here, the authors investigate this question by collecting longitudinal molecular, physical proximity and environmental data in a school in Switzerland.

    • Nicolas Banholzer
    • James Daniel Munday
    • Lukas Fenner
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • Epidemiological estimates from wastewater are not biased by testing rates but may be subject to other biases. Here, the authors investigate the impact of variable virus shedding profiles for different SARS-CoV-2 variants on estimates of their selection advantage.

    • David Dreifuss
    • Jana S. Huisman
    • Timothy R. Julian
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-10

  • The diversity of ESBL-producing Klebsiella pneumoniae species complex and ESBL-Escherichia coli within patients is low and colonization with the same strain may persist for long periods. Authors utilise clinical and microbiological data from electronic health records to investigate genetic diversity of colonizing and infecting strains.

    • Lisandra Aguilar-Bultet
    • Ana B. García-Martín
    • Sarah Tschudin-Sutter
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Chemoselective dual functionalization of proteins is an invaluable tool to introduce two distinct payloads to proteins. Here, the authors present N-alkylpyridinium reagents as soft electrophiles for chemoselective dual modification of cysteine residues in peptides or proteins via a 1,6-addition reaction.

    • Lujuan Xu
    • Maria J. S. A. Silva
    • Tanja Weil
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • Geographical hotspots with high frequency of multi-drug resistant tuberculosis (MDR-TB) have been observed in several locations, such as the country of Georgia. Here, the authors analyse genomic sequences from tuberculosis bacteria isolated from Georgia to show that the transmission fitness of MDR-TB strains is heterogeneous, and highly drug-resistant and transmissible isolates contribute to the emergence and maintenance of MDR-TB hotspots.

    • Chloé Loiseau
    • Etthel M. Windels
    • Sebastien Gagneux
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11

  • We know that variations in cell cycle duration between cells naturally occur but the mechanisms are largely unknown. Here, using lineage tracking, hierarchical clustering and Monte Carlo methods, the authors show that large differences in granddaughter cell cycle duration are driven by asymmetric divisions.

    • Ulrich Berge
    • Daria Bochenek
    • Ruth Kroschewski
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • Reconstructions of evolutionary history from molecular vs. fossil data are often in conflict. Here, the authors show that discrepancies in speciation and extinction rates can arise from differing assumptions about underlying processes and present a model that reconciles fossil and molecular evidence.

    • Daniele Silvestro
    • Rachel C. M. Warnock
    • Tanja Stadler
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14

  • Analysis of the spread of the 20E (EU1) variant of SARS-CoV-2 through Europe suggests that international travel and insufficient containment, rather than increased transmissibility, led to a resurgence of infections.

    • Emma B. Hodcroft
    • Moira Zuber
    • Richard A. Neher
    Research
    Nature
    Volume: 595, P: 707-712

  • A model-based approach allows quantification of lineage-specific speciation and extinction rates on the basis of phylogenetic trees.

    • Tanja Stadler
    News & Views
    Nature Ecology & Evolution
    Volume: 3, P: 1003-1004

  • Ecosystem services provided by dung beetles are an underappreciated component of terrestrial ecosystems. Here, the authors report a standardized distributed experiment which shows that dung removal rate, a key ecosystem process in pastures, is greater under high beetle functional diversity regardless of grazing intensity.

    • Jorge Ari Noriega
    • Joaquín Hortal
    • Ana M. C. Santos
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11

  • Paul Pharoah and colleagues report the results of a large genome-wide association study of ovarian cancer. They identify new susceptibility loci for different epithelial ovarian cancer histotypes and use integrated analyses of genes and regulatory features at each locus to predict candidate susceptibility genes, including OBFC1.

    • Catherine M Phelan
    • Karoline B Kuchenbaecker
    • Paul D P Pharoah
    Research
    Nature Genetics
    Volume: 49, P: 680-691

  • Recent advances in genome engineering are enabling the recording of cellular histories into genomes, with single-cell and spatial omics technologies enabling their reconstruction into cellular lineages, states and exposures. This Perspective explores the rationale and technical basis of DNA recording, what aspects of cellular biology can be recorded and how, and the types of discovery that DNA recording will enable when studying development and disease.

    • Amjad Askary
    • Wei Chen
    • Martin Tran
    Reviews
    Nature Reviews Genetics
    Volume: 26, P: 203-222

  • In this study, the authors provide a global overview of SARS-CoV-2 genome sequencing, and estimate the proportion of cases sequenced and time to genome upload. They identify disparities and highlight the need to strengthen surveillance in lower and middle income countries.

    • Anderson F. Brito
    • Elizaveta Semenova
    • Nuno R. Faria
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • Synthetic approaches that can simultaneously control both polymer sequence and dispersity are difficult to achieve. Now, a switchable RAFT agent that regulates chain transfer activity during controlled radical polymerization has been shown to enable the one-pot synthesis of sequence-controlled multiblocks with on-demand control over dispersity while maintaining high livingness.

    • Maria-Nefeli Antonopoulou
    • Richard Whitfield
    • Athina Anastasaki
    Research
    Nature Chemistry
    Volume: 14, P: 304-312

  • A study using phylodynamics to investigate highly pathogenic avian influenza (HPAI) H5N8 spread in southwestern France in 2020 and 2021 demonstrates that a single introduction led to rapid spread, mainly in duck farms, with farm density driving transmission.

    • Claire Guinat
    • Cecilia Valenzuela Agüí
    • Timothée Vergne
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-8

  • This Perspective considers the application to infectious disease modelling of AI systems that combine machine learning, computational statistics, information retrieval and data science.

    • Moritz U. G. Kraemer
    • Joseph L.-H. Tsui
    • Samir Bhatt
    Reviews
    Nature
    Volume: 638, P: 623-635