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  • Treatment of KRASG12C-mutant cancer cells with the KRAS(G12C) inhibitor AMG 510 leads to durable response in mice, and anti-tumour activity in patients suggests that AMG 510 could be effective in patients for whom treatments are currently lacking.

    • Jude Canon
    • Karen Rex
    • J. Russell Lipford
    Research
    Nature
    Volume: 575, P: 217-223