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Showing 1–4 of 4 results
Advanced filters: Author: Taras A. Redchuk Clear advanced filters

  • Optogenetic approaches to control protein-protein interactions usually require overexpression of the target proteins. Here the authors integrate intrabodies into near-infrared- and blue-light activatable optogenetic tools to control endogenous proteins in mammalian cells.

    • Taras A. Redchuk
    • Maksim M. Karasev
    • Vladislav V. Verkhusha
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • The engineering of Q-PAS1, a single-domain variant of PpsR2, led to an optimized optogenetic system based on the Q-PAS1–BphP1 interaction, which was applied to the regulation of transcription, epigenetic state and protein localization by near-infrared light.

    • Taras A Redchuk
    • Evgeniya S Omelina
    • Vladislav V Verkhusha
    Research
    Nature Chemical Biology
    Volume: 13, P: 633-639