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Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response

Aging is associated with a loss of blood stem cell fitness in part due to defects in stem cell-supportive niches. Here, the authors demonstrate that restoring niche function by treatment with Netrin-1 is able to rejuvenate aged blood stem cells.

Pradeep Ramalingam
Michael C. Gutkin
Jason M. Butler
ResearchOpen Access10 Apr 2023
Nature Communications

Volume: 14, P: 1-20
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Amendments and Corrections22 May 2024
Nature Medicine

Volume: 30, P: 2091
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Amendments and Corrections14 Nov 2023
Nature Medicine

Volume: 30, P: 603
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Amendments and Corrections13 Dec 2023
Nature Medicine

Volume: 30, P: 605
A joint international consensus statement for measuring quality of survival for patients with childhood cancer

The International Childhood Cancer Outcome Project group, involving survivors and other relevant stakeholders, develop a set of core outcomes to measure the quality of care for 17 types of childhood cancers.

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Reviews15 Jun 2023
Nature Medicine

Volume: 29, P: 1340-1348

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Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response

Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

A joint international consensus statement for measuring quality of survival for patients with childhood cancer

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