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Advanced filters: Author: Telma Ventura Clear advanced filters

  • Hematopoietic stem cells are supported by niche cells that help balance stem cell self-renewal and differentiation. Here they show that Runx1 deletion in the embryonic perivascular HSC niche impairs hematopoietic development in vivo and causes transcriptional changes in pericytes/vSMCs, endothelial cells and hematopoietic cells in the murine AGM.

    • Zaniah N. Gonzalez Galofre
    • Alastair M. Kilpatrick
    • Mihaela Crisan
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17