Highly porous star-shaped polyhedral oligomeric silsesquioxane (POSS) hybrid films were synthesized using POSS as the starting core followed by polycaprolactone (PCL) extension and polyurethane (PU) cross-linking. The unique three-dimensional nanotopography of these films is conducive for cell growth. The combination of favorable factors such as high porosity, reactive surface topography, excellent biocompatibility and biphasic degradation makes the star-shaped POSS-PCL-PU film a great candidate as a tissue engineering scaffold biomaterial.
- Choon Peng Teng
- Khine Yi Mya
- Ming-Yong Han
