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Showing 1–2 of 2 results
Advanced filters: Author: Teun Munnik Clear advanced filters

  • Plant cells maintain strict proton gradients over different membranes. Here, Dejonghe et al. show that several protonophores, including the known tyrosine kinase inhibitor TyrphostinA23, inhibit clathrin-mediated endocytosis by disturbing these gradients and causing cytoplasmic acidification.

    • Wim Dejonghe
    • Sabine Kuenen
    • Eugenia Russinova
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12

  • PI(4,5)P2 is importantly involved in a broad array of cellular processes, including polar auxin transport, vesicle trafficking and anisotropic cell growth. An inducible system is developed in Arabidopsis to conduct tunable depletion of PI(4,5)P2 and reveal new roles of this membrane lipid.

    • Mehdi Doumane
    • Alexis Lebecq
    • Marie-Cécile Caillaud
    Research
    Nature Plants
    Volume: 7, P: 587-597