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Showing 1–3 of 3 results
Advanced filters: Author: Thanmayi Ranganath Clear advanced filters

  • There is a genetic component to the risk of severe COVID-19, but the genetic effects are difficult to separate from social constructs that covary with genetic ancestry. To address this, the authors identify determinants of COVID-19 severity using admixture mapping, viral phylodynamics, and host immune and metagenomic sequencing.

    • Victoria N. Parikh
    • Alexander G. Ioannidis
    • Euan A. Ashley
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • Single-cell transcriptomic analysis identifies changes in peripheral immune cells in seven hospitalized patients with COVID-19, including HLA class II downregulation, a heterogeneous interferon-stimulated gene signature and low pro-inflammatory cytokine gene expression in monocytes and lymphocytes.

    • Aaron J. Wilk
    • Arjun Rustagi
    • Catherine A. Blish
    Research
    Nature Medicine
    Volume: 26, P: 1070-1076