Abnormal, misfolded tau proteins are found in cognitively normal individuals and Tauopathies, suggesting not all tau species are pathogenic. Here, the authors show tau seeding and post-translational modification profiles were associated with Aβ neuritic plaque density and differentiated two tauopathies.
- Danielle F. Browne
- Denis S. Smirnov
- Allison Kraus