Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: Thijs J. Beldman Clear advanced filters

  • Delivering immunomodulatory compounds to myeloid cells can activate innate immunity for cancer immunotherapy. Here the authors design a polymersome-based nanocarrier for delivering β-glucan to red pulp myeloid cells in the spleen and show that their strategy achieves tumour growth reduction in a melanoma model.

    • Annelies C. Wauters
    • Jari F. Scheerstra
    • Jan C. M. van Hest
    ResearchOpen Access
    Nature Nanotechnology
    Volume: 19, P: 1735-1744

  • Cytokines are key regulators of the immune system and can be recombinantly designed as therapeutics for immune-related disorders. However, the severe toxicity of recombinant cytokines limits their clinical translation. In this Review, the authors highlight bioengineering approaches for the design of clinically applicable and safe cytokine-based therapeutics.

    • Jeroen Deckers
    • Tom Anbergen
    • Willem J. M. Mulder
    Reviews
    Nature Reviews Bioengineering
    Volume: 1, P: 286-303

  • Trained immunity is a form of nonspecific immune memory, harboured within the innate immune system. This Review discusses nanomedicine platforms to therapeutically regulate trained immunity for the treatment of various conditions, including cancer, inflammation and infection.

    • Mandy M. T. van Leent
    • Bram Priem
    • Willem J. M. Mulder
    Reviews
    Nature Reviews Materials
    Volume: 7, P: 465-481