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Showing 1–3 of 3 results
Advanced filters: Author: Thilo Kalbhenn Clear advanced filters

  • A battery of bedside tests was designed to test split-brain patients across multiple functional domains. While full callosotomy introduced disconnection syndromes across all domains, even minimal callosal remnants enabled fully integrated behavior.

    • Selin Bekir
    • Johanna L. Hopf
    • Michael B. Miller
    ResearchOpen Access
    Communications Psychology
    Volume: 4, P: 1-11

  • Whether and how slow wave activity (SWA) and the underlying membrane potential UP and DOWN states initiate mechanisms that augment memory functions in humans are not fully understood. Here authors used multineuron patch-clamp in alive human brain tissue, resected during neurosurgeries, to show that membrane potential UP/DOWN states, which mimic neural sleep activity, modulate axonal action potentials to boost synaptic strength and plasticity.

    • Franz X. Mittermaier
    • Thilo Kalbhenn
    • Jörg R. P. Geiger
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11

  • Somatic variants in certain genes can cause lesional focal epilepsy. Here the authors perform the largest somatic variant detection study in epilepsy to date, finding statistical support for 8 known and 2 novel genes, DYRK1A and EGFR, which may be potential biomarkers and druggable targets.

    • Christian M. Boßelmann
    • Costin Leu
    • Dennis Lal
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-10